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Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Sonic hedgehog proteins may help grow hair.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Hedgehog signaling controls hair follicle development and can affect skin cancer growth.

New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Laser hair-comb therapy doesn't improve male-pattern hair loss.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

The document covers various dermatological conditions and their studies.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.