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    Did you mean Progesterone Receptor?
    Glossary Progesterone Receptor

    protein in cells that binds to the hormone progesterone

    The Progesterone Receptor (PR) is a protein found inside cells that binds to the hormone progesterone. This receptor is crucial for regulating various reproductive processes, including the menstrual cycle and pregnancy. In the context of hair and alopecia, PRs can influence hair growth cycles and are a target for treatments aimed at conditions like androgenetic alopecia.

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    1. Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified Experimental Dermatology · 2012 · 18 citations
    2. Pharmacology of different progestogens: the special case of drospirenone Climacteric · 2005 · 104 citations
    3. The effects of sex-steroids and menstrual cycle/oestrous phases on knee ligament laxity in humans and rodents / Firouzeh Dehghan 2014
    4. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004 · 180 citations
    5. Anesthetic effects of progesterone are undiminished in progesterone receptor knockout mice Brain Research · 2005 · 35 citations
    6. Sex Steroid Hormone Receptors in Human Skin Appendage and its Neoplasms Endocrine Journal · 2005 · 59 citations
    7. Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice International Journal of Molecular Sciences · 2025 · 4 citations
    8. Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding International Journal of Molecular Sciences · 2014 · 23 citations
    9. Anxiolytic activity of progesterone in progesterone receptor knockout mice Neuropharmacology · 2004 · 151 citations
    10. Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia Research and Reports in Urology · 2019 · 26 citations
    11. PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields Brain research · 2017 · 14 citations
    12. Relating neurosteroid modulation of inhibitory neurotransmission to behaviour Journal of Neuroendocrinology · 2021 · 18 citations
    13. Kelulut Honey Regulates Sex Steroid Receptors in a Polycystic Ovary Syndrome Rat Model International Journal of Molecular Sciences · 2022 · 1 citations
    14. Roles of steroid receptors in the lung and COVID-19 Essays in Biochemistry · 2021 · 9 citations
    15. Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs Journal of Dermatological Science · 2012 · 1 citations
    16. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    17. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    18. Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function Molecular Medicine · 2004 · 31 citations
    19. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    20. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    21. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    22. A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity The Journal of Clinical Endocrinology & Metabolism · 2005 · 91 citations
    23. Androgen Receptor Ligands: Agonists and Antagonists Elsevier eBooks · 2017 · 2 citations
    24. Androgens and androgen receptor action in skin and hair follicles Molecular and Cellular Endocrinology · 2017 · 100 citations
    25. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    26. Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus) The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 58 citations
    27. Chapter 17. Selective androgen receptor modulators (SARMs) Annual Reports in Medicinal Chemistry · 2001 · 18 citations
    28. Androgen Receptor in Human Health: A Potential Therapeutic Target Current Drug Targets · 2012 · 12 citations
    29. Androgen receptors and their biology Vitamins and hormones · 2001 · 66 citations
    30. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations