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Glossary Primary Closure

method of directly closing wound edges for optimal healing

Primary closure refers to the method of closing a wound by bringing the edges together directly, usually with sutures, staples, or adhesive. This technique is often used in surgical procedures, including hair transplant surgeries, to promote faster healing and minimize scarring. For professionals, it is crucial to ensure that the wound edges are well-aligned to optimize the healing process and aesthetic outcome.

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research The Surgical Management of Extensive Cases of Acne Keloidalis Nuchae

72 citations , November 2000 in “Archives of Dermatology”

This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.

Scalp Reconstruction Techniques After Oncologic Resection

research Scalp reconstruction

66 citations , October 2006 in “Journal of Surgical Oncology”

This review discusses current techniques for scalp reconstruction following oncologic surgery and reports no new clinical outcomes, emphasizing the importance of tailored approaches for satisfactory closure.

research Surgical Management of Scalp Infantile Hemangiomas

15 citations , June 2015 in “Journal of Craniofacial Surgery”

This study suggests that surgical intervention for scalp infantile hemangiomas, often necessary due to complications like alopecia and ulceration, generally leads to good aesthetic outcomes and satisfactory hair growth.

research Obliteration of alopecia by hair-lifting: a new concept and technique.

7 citations , September 1977 in “PubMed”

This article describes a new surgical technique called "hair-lifting" for treating male-pattern alopecia, which involves removing sections of bald scalp and repositioning remaining hair.

research Revision Surgical Hair Restoration: Repair of Undesirable Results

5 citations , July 1999 in “Plastic and Reconstructive Surgery”

This study found that reparative surgical techniques significantly improved the appearance of patients dissatisfied with previous hair restoration procedures, with minor and correctable complications.

research The Use of the Juri Temporo-Parieto-Occipital Flap

2 citations , May 2005 in “Seminars in Plastic Surgery”

This article discusses the temporo-parieto-occipital flap for scalp reconstruction and reports no new clinical results; the authors emphasize its specific reconstructive indications.

research Scalp and calvarial reconstruction

1 citations , March 2015

This article reviews surgical techniques for addressing scalp defects and highlights hair restoration as a cosmetic improvement strategy, but it reports no new clinical results.

research Review Article: Post-Trauma Scalp Reconstruction

October 2025 in “International Journal of Medical Science and Clinical Research Studies”

In this systematic review, the researchers provide an overview of recent techniques and innovations in the surgical reconstruction of traumatic scalp injuries, highlighting various methods and factors influencing the choice of reconstructive strategy to improve patient outcomes.

research An algorithmic approach to scalp reconstructive surgery: maximization of cosmetic and functional outcomes

April 2024 in “Archives of Dermatological Research”

This research review explores an algorithmic approach to scalp reconstruction, emphasizing the importance of considering defect location, size, and local scalp anatomy in optimizing cosmetic and functional surgical outcomes.

research Recurrent pseudolymphomatous reaction to ear piercing: 20-year history

October 2023 in “Pathology”

In this study, the authors observed that a 48-year-old woman developed a cutaneous pseudolymphoma in the earlobes linked to metallic debris from ear piercing, which histologically mimicked lymphoma but was interpreted as a reactive condition.

research Scalp reconstructive flaps

January 2022 in “Plastic and Aesthetic Research”

This review explores techniques for scalp reconstruction, focusing on local flap design and execution, without reporting new clinical findings.

research Aesthetic Considerations in Scalp Reconstruction

19 citations , February 2008 in “Facial Plastic Surgery”

This article reviews various reconstructive surgery techniques for scalp wounds and emphasizes factors affecting aesthetic outcomes, but it presents no new clinical findings.

research Angle closure in fellow eye with prophylactic pilocarpine treatment

13 citations , October 2001 in “British Journal of Ophthalmology”

This report discusses the use of intralesional cidofovir and suggests it might be a viable option for treating SCC due to its successful outcome without observed systemic toxicity in this case.

Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing

research Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing

32 citations , March 2014 in “PLOS ONE”

This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.

research Scalp Flaps

20 citations , February 1991 in “The Journal of Dermatologic Surgery and Oncology”

This article discusses scalp reconstruction techniques using rotation flaps, with no new clinical results reported.

research 1372 Modulation of YBX1 phosphorylation determines epidermal stem cell function

April 2023 in “Journal of Investigative Dermatology”

This study found that inhibiting PI3 kinase in epidermal stem cells reduces YBX1 phosphorylation, thereby decreasing cellular senescence and enhancing wound healing and regeneration in adult-derived skin models.

Additional Intraoperative Autologous-Derived Platelet-Rich Stroma to Transanal Flap Repair for the Treatment of Cryptoglandular Transsphincteric Fistulas in a Tertiary Referral Center: Long-Term Outcomes of a Prospective Pilot Study

research Additional Intraoperative Autologous-Derived Platelet-Rich Stroma to Transanal Flap Repair for the Treatment of Cryptoglandular Transsphincteric Fistulas in a Tertiary Referral Center: Long-Term Outcomes of a Prospective Pilot Study

January 2025 in “Bioengineering”

This study evaluated the long-term effects of combining autologous platelet-rich stroma injection with transanal advancement flap repair for cryptoglandular transsphincteric fistulas and found that it resulted in primary clinical closure and radiological healing in a high percentage of patients, with low recurrence rates.

research Pathophysiology of the Burn Scar

10 citations , January 2018 in “Elsevier eBooks”

This review discusses the wound healing process and the factors contributing to abnormal scarring after thermal injuries, but it reports no new clinical results.

research The Sacred Heart Bilobed Flap

1 citations , May 2015 in “Plastic and Reconstructive Surgery”

This article discusses the Sacred Heart version of the bilobed flap for scalp reconstruction to close small defects without skin grafts and reports no new clinical results.

Efficacy and Safety of Autologous Adipose-Derived Stromal Vascular Fraction Enriched with Platelet-Rich Plasma in Flap Repair of Transsphincteric Cryptoglandular Fistulas

research Efficacy and safety of autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma in flap repair of transsphincteric cryptoglandular fistulas

16 citations , October 2021 in “Techniques in Coloproctology”

This study found that using autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma may improve healing rates in patients undergoing flap repair for transsphincteric cryptoglandular fistulas.

research Surgical excision of acne keloidalis nuchae with secondary intention healing

24 citations , October 2007 in “Clinical and experimental dermatology”

This case report describes two men with acne keloidalis nuchae who experienced successful outcomes with excision followed by secondary intention healing, resulting in good cosmetic results and minimal recurrence.

research Management of Avulsive Soft Tissue Ballistic Facial Injuries

February 2025 in “Seminars in Plastic Surgery”

This review addresses the complex process of reconstructing gunshot-induced facial injuries, highlighting advancements in composite tissue transplants and allografts that enhance plastic surgeons' ability to achieve optimal aesthetic and functional outcomes despite significant challenges.

research Skin Graft Harvesting and Donor Site Selection

3 citations , August 2011 in “InTech eBooks”

This article discusses the applications and contraindications of skin grafts in wound treatment and reports no new research findings.

research Desmoplastic melanoma presenting as an alopecic patch in a young patient

June 2023 in “JAAD Case Reports”

This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.

research Four Closure

September 2013 in “Science”

Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.

research Management of primary cicatricial alopecias: options for treatment

98 citations , May 2008 in “British Journal of Dermatology”

This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.

research Primary cicatricial alopecia

65 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.

research Primary Cicatricial Alopecias

18 citations , October 2012 in “Dermatologic Clinics”

This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.

research Primary cicatricial alopecias

1 citations , April 2010 in “Expert Review of Dermatology”

This review discusses primary cicatricial alopecias, detailing their classification, pathogenesis, clinical features, histopathologic findings, and treatment, without reporting new experimental results.

research Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

19 citations , August 2012 in “Cell death and differentiation”

This study found that disrupting the inturned gene in developing mouse epidermis halted hair follicle formation due to impaired keratinocyte differentiation, highlighting primary cilia's role in tissue-specific planar cell polarity signaling.