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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Finasteride effectively treats frontal hair loss with few side effects.

Researchers created human hair follicles using a new method that could help treat hair loss.

Sulforaphane from broccoli can help protect skin from sun damage.

Special fiber materials boost the healing properties of certain stem cells.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Finasteride helps hair growth but may cause sexual side effects.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Probiotic bacteria improved skin and hair health in aged mice.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.