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    Glossary Post-Translational Modifications

    chemical changes to proteins after synthesis affecting their function

    Post-Translational Modifications (PTMs) refer to the chemical changes that proteins undergo after they are synthesized in a cell. These modifications can include the addition of phosphate groups, sugars, or lipids, and they play a crucial role in regulating protein function, stability, and interactions. PTMs are essential for the proper functioning of proteins and can impact various biological processes, including cell signaling, immune responses, and hair growth.

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    1. Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications Frontiers in immunology · 2022 · 11 citations
    2. Foxp3 Post-translational Modifications and Treg Suppressive Activity Frontiers in Immunology · 2019 · 82 citations
    3. A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis that Catalyses the Peptidyl-Arginine-Citrulline Post-translational Modification Current problems in dermatology · 2015 · 3 citations
    4. Entdeckung von Autoantigenen bei der Haarverluststörung Alopecia areata: Implikation von posttranslationalen Modifikationen Karger Kompass. Dermatologie · 2023
    5. Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis 1987 · 81 citations
    6. The proteomics of keratin proteins Journal of Chromatography B · 2006 · 62 citations
    7. Genetic Analysis of Androgen Receptors in Development and Disease Advances in pharmacology · 1999 · 44 citations
    8. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    9. Proteomic analysis of hair shaft and nail plate. PubMed · 2011 · 29 citations
    10. From gene to therapy in spinal and bulbar muscular atrophy: Are we there yet? Molecular and Cellular Endocrinology · 2017 · 17 citations
    11. Common pathologic pathways: A single prescription dream? Medical Hypotheses · 2012 · 1 citations
    12. A Clinical Review of Trichorrhexis Nodosa The Open Dermatology Journal · 2025
    13. https://researchopenworld.com/genetics-of-hidradenitis-suppurativa/# 2020
    14. Modulation of Androgen Receptor Transcriptional Activity RePub (Erasmus University Rotterdam) · 2009
    15. Wound Healing Mechanisms American Journal of Nursing · 1982
    16. The role of protein lactylation in skin diseases: from molecular mechanisms to potential therapeutics Frontiers in Immunology · 2026
    17. The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles Science Advances · 2025
    18. Correction of the Cornrow Transplant and Other Common Problems in Surgical Hair Restoration Plastic and Reconstructive Surgery · 2000 · 4 citations
    19. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018 · 211 citations
    20. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006 · 122 citations
    21. Skin Keratins 2015 · 54 citations
    22. Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments Analytical biochemistry · 2011 · 38 citations
    23. Keratin function and regulation in tissue homeostasis and pathogenesis Biomolecular concepts · 2012 · 7 citations
    24. A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins Biophysical journal · 2022 · 5 citations
    25. Ribonucleic Acids Coding for the Keratin Complex of Hair 1981 · 5 citations
    26. 120 Identification of post-translationally modified trichohyalin epitopes responsible for triggering autoimmunity in alopecia areata Journal of Investigative Dermatology · 2023
    27. Progress in the Expression, Purification, and Characterization of Recombinant Collagen Bioengineering · 2026
    28. The Fate of Trichohyalin 1997 · 135 citations
    29. Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses Biomolecules · 2025
    30. Is There a Histone Code for Cellular Quiescence? Frontiers in Cell and Developmental Biology · 2021 · 27 citations