Search
for

    Did you mean Polygenic Risk Score?
    Glossary Polygenic Risk Score

    numerical estimate of genetic predisposition based on multiple variants

    A Polygenic Risk Score (PRS) is a numerical value that estimates an individual's genetic predisposition to a particular trait or disease, based on the cumulative effect of multiple genetic variants. By analyzing data from genome-wide association studies (GWAS), researchers can calculate a PRS to predict the likelihood of conditions such as alopecia, heart disease, or diabetes, providing valuable insights for personalized medicine and preventive healthcare.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Human Genomics · 2024 · 1 citations
    2. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Research Square (Research Square) · 2023
    3. Evidence for a polygenic contribution to androgenetic alopecia British Journal of Dermatology · 2013 · 26 citations
    4. Reconsidering the Polycystic Ovary Syndrome (PCOS) Biomedicines · 2022 · 41 citations
    5. Analysis of 72,469 UK Biobank exomes links rare variants to male-pattern hair loss Nature Communications · 2023
    6. Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism · 2023
    7. What Is the Male Polycystic Ovary Syndrome Phenotype? 2021
    8. Systematic investigation of a potential epidemiological and genetic association between male androgenetic alopecia and COVID‐19 Skin health and disease · 2021 · 2 citations
    9. A Genetically Defined Male Counterpart of Polycystic Ovary Syndrome: Evidence for Ovarian-Independent Pathogenesis Journal of the Endocrine Society · 2021 · 2 citations
    10. Dermatological diseases from a genetic perspective Medizinische Genetik · 2023
    11. Do Alopecia Areata and Hair Colour Have a Shared Genetic Component? Experimental Dermatology · 2026
    12. Longitudinal Assessment of the Prevalence of Actinic Keratosis and Extensive Risk Factor Evaluation: An Update from the Rotterdam Study Journal of Investigative Dermatology · 2023 · 10 citations
    13. Multi-ancestry tandem repeat association study of hair colour using exome-wide sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2024
    14. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    15. Etiopathogenesis of Alopecia Areata Hair therapy & transplantation · 2014 · 2 citations
    16. The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives Biology · 2026
    17. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report Fertility and Sterility · 2008 · 1540 citations
    18. GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk Nature Communications · 2017 · 57 citations
    19. Comparative Evaluation of Oral Baricitinib and Tofacitinib in Alopecia Areata: A Retrospective Cohort Study Based on SALT Scores Turkish Journal of Dermatology · 2025
    20. Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris European Journal of Human Genetics · 2023 · 29 citations
    21. Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University) · 2010
    22. Why are men with premature alopecia at higher risk of benign prostatic hyperplasia? And what about prostate cancer? Expert Review of Dermatology · 2012
    23. Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer European Journal of Cancer · 2010 · 28 citations
    24. Polycystic ovary syndrome: Pathophysiology, Symptoms, Risk factors, and Pharmacological treatment Research Journal for Social Affairs · 2024
    25. Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress Medicine Science | International Medical Journal · 2021
    26. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness Nature Communications · 2018 · 58 citations
    27. Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-analysis Acta dermato-venereologica · 2023 · 10 citations
    28. Alopecia areata: An update Indian Journal of Dermatology, Venereology and Leprology · 2013 · 67 citations
    29. Female pattern hair loss Indian Journal of Dermatology, Venereology and Leprology · 2013 · 23 citations
    30. Bridging psychoneuroimmunology and homeopathy: Modulating the cellular and emotional cascades in refractory alopecia International Journal of Homoeopathic Sciences · 2026