October 2023 in “Research Review” The document discusses cutaneous tumors of pilar origin, which develop from skin appendages like hair follicles and sebaceous glands. These tumors can be benign or malignant and may be associated with genetic syndromes. Benign neoplasms include Trichoblastoma, Pilomatricoma, Trichilemmoma, Trichofolliculoma, and Fibrofolliculoma, while malignant ones include Pilomatriceal carcinoma and proliferating trichilemmal tumors. Malignant tumors are rare but can be locally aggressive with potential for nodal involvement and distant metastasis. The tumors are categorized based on follicular differentiation, and several syndromes linked to these tumors involve gene abnormalities.
September 2020 in “Acta Scientific Cancer Biology” Personalized treatment based on detailed tumor analysis successfully managed and reduced the patient's aggressive hair follicle cancer.
2 citations,
November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
December 2021 in “Pathologica” Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.
7 citations,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
November 2011 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Polyomavirus A2 infection in newborn mice caused hair follicle tumors.
4 citations,
August 2017 in “International journal of molecular sciences” The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
13 citations,
June 2018 in “Dermatopathology” A new classification system for skin cysts was proposed to improve diagnosis.