research Cutaneous Manifestations of Systemic Lupus Erythematosus
Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.
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research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
research Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Follicular Targeting: A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Drug Reactions Affecting Hair: Diagnosis
Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.
research A Dubious Equality: Men, Women, and Cosmetic Surgery
The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Cultured Human and Rat Tooth Papilla Cells Induce Hair Follicle Regeneration and Fiber Growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Inherited Ichthyosis: Syndromic Forms
Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
research Hair Shaft Abnormalities: Clues to Diagnosis and Treatment
Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss
Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research An Ultrastructural Study of Hair Fiber Damage and Restoration Following Treatment with Permanent Hair Dye
Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.
research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth
Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
research Comparison of Clinical and Laboratory Characteristics of Cases with Polycystic Ovarian Syndrome Based on Rotterdam’s Criteria and Women with Only Oligo/Anovulation or Hirsutism
Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
research Mouse Models for the Study of Human Hair Loss
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
research Exogen Hair Characterization in Human Scalp
The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Contact Dermatitis to Minoxidil
Minoxidil can cause skin irritation like eczema and rash in some users.
research The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism
Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
research Androgenic Alopecia Is Not Useful as an Indicator of Men at High Risk of Prostate Cancer
Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons
Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Foliar and Root Applications of Vegetal-Derived Protein Hydrolysates Differentially Enhance the Yield and Qualitative Attributes of Two Lettuce Cultivars Grown in Floating System
Protein hydrolysates applied to roots or leaves differently improved lettuce yield and quality, with the best results seen in specific combined treatments for each type.