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Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

New materials and methods could improve skin healing and reduce scarring.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Pregnancy can cause more body and scalp hair growth and make nails brittle, but these changes often revert after giving birth.

Finasteride reduces prostate cancer risk but may increase high-grade tumors and has side effects; biopsy methods have similar outcomes; psychosocial factors affect sexual recovery post-surgery.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

A 62-year-old woman with hair loss and skin condition had successful hair transplant surgery lasting 6 years, and medications helped reduce hair fall and promote growth.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The Rotterdam Study aims to understand various diseases in older adults.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.