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Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Hair-thread Tourniquet Syndrome, where hair or thread tightly wraps around a body part, is not rare and requires early detection to prevent serious damage.

Finasteride temporarily lowers male rat fertility without affecting libido.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

The critique highlights an error in a review about hair loss treatment, stressing the need for accurate information and caution due to poor evidence quality.

A woman developed male traits from accidental contact with her husband's testosterone gel.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Metabolic syndrome linked to urinary symptoms; hair loss not significant.