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Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Advanced human skin models improve drug development and could replace animal testing.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Msx2 and Foxn1 are both crucial for hair growth and health.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

No cure for female pattern hair loss, but various effective treatments exist.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.