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Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

New genes and pathways are important for testosterone production and male sexual development.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Some chemotherapy can cause permanent hair loss.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.