January 1984 in “Isotopenpraxis Isotopes in Environmental and Health Studies” This study determined the levels of several elements including iodine and bromine in hair samples from patients with various thyroid diseases compared to control groups without such conditions.
99 citations
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May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers propose that the EDAR V370A allele's positive selection in East Asian populations may be linked to stable aquatic resources from Late Pleistocene ecosystems in northern China, suggesting a "nutritional niche construction" framework where these resources offset the allele's metabolic costs.
28 citations
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August 2000 in “Current Opinion in Chemical Biology” This article reviews current osteoporosis treatments, focusing on the potential of selective androgen receptor modulators and other agents to enhance bone formation, but provides no new clinical data.
11 citations
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July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This review discusses the role of oestrogens in stimulating linear bone growth and pubertal changes in both boys and girls, highlighting their influence on the growth hormone-insulin-like growth factor axis; it reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents a hypothesis that the EDAR V370A allele was positively selected in East Asian populations due to the stable aquatic resources in Late Pleistocene northern China, which may have offset the allele's metabolic costs and provided a selective advantage.
51 citations
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March 1986 in “Acta Dermato Venereologica” This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.
4 citations
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January 2010 This study found significant reductions in zinc, copper, and iron levels in patients with idiopathic telogen effluvium compared to healthy controls, suggesting a potential role for trace element deficiency in the condition.
61 citations
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September 1970 in “Journal of the American Geriatrics Society” In this study, anabolic and catatoxic steroids were reported to prevent weight loss, tissue calcification, and cardiac necrosis in a rat model of disturbed calcium metabolism and progeria-like syndrome.
9 citations
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August 2024 in “Journal of Orthopaedic Translation” This study suggests that bioactive ceramics could be an effective universal strategy for treating musculoskeletal disorders by targeting the Piezo1-modulated intracellular calcium pathway during bone and muscle formation.
5 citations
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November 2024 in “Advanced Science” This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.
28 citations
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December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
1 citations
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December 2015 in “Lʹvìvsʹkij klìnìčnij vìsnik” This review discusses the connection between alopecia areata and trace element imbalances, noting deficiencies in elements like zinc and selenium, but reports no new clinical findings.
15 citations
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March 1987 in “Phycologia” This study found that phosphorus limitation in Chaetophorales strains led to enhanced hair formation and increased phosphatase activity, suggesting a significant relationship between phosphorus status and morphology.
June 2025 in “Histopathology” This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.
1 citations
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February 2013 in “Steroids” In this study, a deproteinized bone mineral showed potential to increase DHT production, suggesting an anabolic effect on human periosteal fibroblasts with possible implications for wound healing.
9 citations
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January 2014 in “Journal of analytical & bioanalytical techniques” This study assessed whether the elemental composition of human hair could serve as a marker for kidney stones, cholelithiasis, hypertension, and diabetes, but it reports only variations in element content along hair regions.
October 2008 in “Trace Elements and Electrolytes” In this study, perimenopausal women with initially high hair concentrations of calcium, magnesium, and silicon experienced a decrease in these elements after intermittent dietary supplementation with calcium, magnesium, silicon, and vitamin D.
This systematic review and meta-analysis found that patients with telogen effluvium, primarily females, exhibited significantly lower serum levels of ferritin and vitamin D compared to healthy controls, suggesting trace element imbalances play a crucial role in this type of hair loss.
August 2009 in “Mechanisms of Development” 5 citations
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August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
January 1994 in “Memorial University Research Repository (Memorial University)” This study suggests that oleosomes in Sesbania nodules are utilized for cell growth and development but are not directly involved in nitrogen fixation.
203 citations
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December 1947 in “Annals of Internal Medicine” This lecture discusses osteoporosis and its connection to internal skeletal dynamics but reports no new research findings.
March 2026 in “Skin Appendage Disorders” This study reviewed multiple research articles and found that patients with telogen effluvium, primarily women, had significantly lower levels of serum ferritin and vitamin D compared to healthy controls, suggesting a role for trace element imbalances in hair loss.
January 1994 in “中医杂志:英文版” This study found that aplastic anemia patients with deficiencies in yin, yang, or both had reduced levels of various trace elements in their hair compared to healthy controls.
March 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that a positive feedback loop involving RHD2, reactive oxygen species, and calcium ions helps maintain root hair growth sites and influences cell shape in Arabidopsis thaliana.
May 2021 in “Research Square” 3 citations
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December 2019 in “Biomaterials Research/Biomaterials research” This study found that the concentrations of major inorganic elements in human scalp hair increase with age up to 25 years, and calcium and magnesium concentrations are significantly associated with sex in individuals over 20.
2 citations
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February 2009 in “Clinical and Experimental Dermatology” In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.
6 citations
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April 1989 in “Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms” Sulphur in hair follicles increases from the bulb and then levels off, while other elements vary in distribution.