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    Glossary NFATc1

    protein regulating gene expression in immune and hair follicle cells

    NFATc1, or Nuclear Factor of Activated T-Cells, cytoplasmic 1, is a protein that plays a crucial role in the regulation of gene expression in immune cells, particularly T-cells. It is involved in the activation of immune responses and has also been implicated in various biological processes, including the development and function of hair follicles.

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    Research 30 of 328

    1. NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008 · 415 citations
    2. Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation Genes & Development · 2014 · 40 citations
    3. Investigation the role of SIRT3, SIRT7, NFATC1, and PDL-1 genes in androgenetic alopecia BMC Research Notes · 2024
    4. Investigation the role of SIRT3, SIRT7, NFATC1, and PDL-1 genes in Androgenetic Alopecia Research Square (Research Square) · 2024
    5. MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata 2023
    6. The Brown Algae Ishige sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis through Downregulation of NFATc1/c-Fos Nutrients · 2022 · 8 citations
    7. Epidermal stem cell diversity and quiescence EMBO molecular medicine · 2009 · 168 citations
    8. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Science · 2016 · 142 citations
    9. Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis PloS one · 2012 · 52 citations
    10. SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice EMBO journal · 2020 · 38 citations
    11. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    12. Re-Evaluating Cyclosporine A as a Hair Growth–Promoting Agent in Human Scalp Hair Follicles Journal of Investigative Dermatology · 2015 · 29 citations
    13. The HPV16 oncogenes cause aberrant stem cell mobilization Virology · 2013 · 23 citations
    14. Regulation of Hair Shedding by the Type 3 IP3 Receptor 2012 · 19 citations
    15. Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X PLOS ONE · 2017 · 18 citations
    16. A New Role for an Old Friend: NFAT and Stem Cell Quiescence Cell stem cell · 2008 · 4 citations
    17. Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets Experimental Dermatology · 2022 · 3 citations
    18. Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of hair follicle stem cells Communications Biology · 2024 · 1 citations
    19. PIEZO1-mediated calcium signaling reinforces mechanical properties of hair follicle stem cells to promote quiescence Science Advances · 2025
    20. 1438 KLF4 maintains hair follicle stem cell quiescence 2023
    21. Distinct tooth regeneration systems deploy a conserved battery of genes bioRxiv (Cold Spring Harbor Laboratory) · 2020
    22. Calcineurin/Nuclear Factor of Activated T-Cell Pathway in Cutaneous Squamous Cell Carcinoma International journal of dermatology and venereology · 2019
    23. Quiescent and aging hair follicle stem cells Science · 2016
    24. Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes American Journal of Physiology-cell Physiology · 2003 · 57 citations
    25. Distinct tooth regeneration systems deploy a conserved battery of genes EvoDevo · 2021 · 16 citations
    26. Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis Calcified Tissue International · 2026
    27. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    28. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    29. Are hair follicle stem cells promising candidates for wound healing? Expert Opinion on Biological Therapy · 2018 · 18 citations
    30. Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018 · 13 citations