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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

PGD2 stops hair growth and is higher in bald men with AGA.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hair loss can cause low self-esteem, anxiety, and depression in men.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.