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Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Hair growth and pigmentation in mice involve specific stages crucial for research.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Androgens can both increase and decrease hair growth in different parts of the body.

PGD2 stops hair growth and is higher in bald men with AGA.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Researchers created human hair follicles using a new method that could help treat hair loss.