research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
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research Structural Abnormalities of the Hair Shaft
The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
research Clinical Aspects and Spectrum of Illness of Toxic Shock Syndrome: Overview
Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.
research Light Microscopy of the Hair: A Simple Tool to Untangle Hair Disorders
Light microscopy is useful for diagnosing different hair disorders.
research Rheumatologic Manifestations of Pregnancy
Pregnancy can cause symptoms similar to rheumatic diseases, making diagnosis difficult, and affects various body systems, requiring careful distinction between normal changes and serious conditions.
research Scientific Opinion on the Tolerable Upper Intake Level for Selenium
Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
research An Overview of the Role of Carboxytherapy in Dermatology
Carboxytherapy is a safe and effective treatment for improving skin appearance and treating various skin conditions, with mild side effects.
research Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Classification and Management of Skin, Hair, Nail, and Mucosal Side Effects of Epidermal Growth Factor Receptor Inhibitors
EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.
research Pathologic Hairpulling, Skin Picking, and Nail Biting
Hairpulling, skin picking, and nail biting cause significant harm and need more research for better treatments.
research Videodermoscopy of the Hyponychium in Nail Bed Psoriasis
Videodermoscopy can help diagnose and monitor nail bed psoriasis.
research Keratin Film Made of Human Hair as a Nail Plate Model for Studying Drug Permeation
Keratin films from human hair can potentially replace human nail plates for drug testing.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Determination of the Efficacy of Terbinafine Hydrochloride Nail Solution in the Topical Treatment of Dermatophytosis in a Guinea Pig Model
Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.
research Nail Changes in Alopecia Areata: An Update and Review
Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia
Mutations in the KRT85 gene cause hair and nail problems.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated with Alopecia Universalis
Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.
research Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma
Targeted therapies for advanced skin cancer often cause hair and nail problems, which need managing to avoid changing the treatment dose.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Colocalization of Cystatin M/E and Its Target Proteases Suggests a Role in Terminal Differentiation of Human Hair Follicle and Nail
Cystatin M/E helps in the final stages of hair and nail formation by controlling certain enzymes.
research Hair and Nail Relationship: A Comparative Study
Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.
research Nail Involvement in Alopecia Areata: A Questionnaire-Based Survey on Clinical Signs, Impact on Quality of Life, and Review of the Literature
Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
research Nail Involvement in Frontal Fibrosing Alopecia
Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
research Cultured Nail Keratinocytes Express Hard Keratins Characteristic of Nail and Hair In Vivo
Lab-grown nail cells show characteristics similar to natural nail and hair.
research Recovery of Nail Dystrophy: Potential New Therapeutic Indication of Tofacitinib
Tofacitinib may help treat nail dystrophy, especially when other treatments fail.
research Twenty Nail Onychomadesis: An Unusual Finding in Cronkhite-Canada Syndrome
A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
research Non-Infectious Inflammatory Disorders of the Nail Apparatus
Nail disorders not caused by infection are common and can look similar, with psoriasis being the most frequent and having specific nail symptoms.
research Effect of Dietary Supplementation with INVERSION Femme on Slimming, Hair Loss, and Skin and Nail Parameters in Women
INVERSION Femme supplement helped women lose weight, reduce hair loss, and improve skin and nail health.