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    Glossary N-cadherin

    protein aiding cell adhesion, crucial for tissue development

    N-cadherin, also known as Neural cadherin or CDH2, is a protein that helps cells stick together, playing a crucial role in the development and maintenance of tissues, especially in the nervous system. It is important for processes like cell signaling, tissue formation, and wound healing, and its dysfunction can be linked to various diseases, including cancer and neurodegenerative disorders.

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    Research 30 of 1000+

    1. Paternal finasteride exposure and its impact on offspring testicular histopathology and intracellular junctions: the role of occludin and N-cadherin Reproductive Biology · 2026
    2. 269 The PPAR-γ modulator, N-acetyl-GED, protects from epithelial-mesenchymal-transition to human hair follicles: Potential relevance for scarring alopecia 2017
    3. DHT deficiency perturbs the integrity of the rat seminiferous epithelium by disrupting tight and adherens junctions Folia Histochemica et Cytobiologica · 2011 · 27 citations
    4. Following fibroblast lineages in dermal development and scars Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München) · 2021
    5. 1380 PPAR-γ modulation as a novel therapeutic strategy for scarring alopecia Journal of Investigative Dermatology · 2018
    6. The variable cell Nature reviews. Molecular cell biology (Print) · 2005
    7. Novel compound heterozygous cadherin 3 mutations in hypotrichosis and juvenile macular dystrophy 2022 · 1 citations
    8. Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells Journal of Biological Chemistry · 2001 · 8 citations
    9. Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle 2001 · 45 citations
    10. Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation Scientific Reports · 2017 · 27 citations
    11. 194 An underlying mechanism of hair loss in acrodermatitis enteropathica Journal of Investigative Dermatology · 2016
    12. The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle 2015 · 15 citations
    13. Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis Nature communications · 2023
    14. 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision Journal of Investigative Dermatology · 2017
    15. Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis 2013 · 29 citations
    16. Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice American Journal of Pathology · 2014 · 8 citations
    17. The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice PLoS Biology · 2026
    18. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    19. Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling Molecular therapy · 2017 · 42 citations
    20. Congenital hair loss disorders: Rare, but not too rare The Journal of Dermatology · 2011 · 41 citations
    21. Role of vitamin D and calcium signaling in epidermal wound healing Journal of endocrinological investigation · 2022 · 15 citations
    22. Stem Cell Competition for Niche Occupancy: Emerging Themes and Mechanisms Stem Cell Reviews and Reports · 2010 · 13 citations
    23. A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling iScience · 2023 · 1 citations
    24. ARHGEF3 Regulates Hair Follicle Morphogenesis 2024
    25. A Missense Mutation in the Cadherin Interaction Site of The Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2005 · 33 citations
    26. Hardwiring Stem Cell Communication through Tissue Structure Cell · 2016 · 82 citations
    27. Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse Journal of Investigative Dermatology · 2009 · 92 citations
    28. Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction iScience · 2024
    29. Effects of hyperbaric oxygen therapy on rat facial skin Human & Experimental Toxicology · 2015 · 2 citations
    30. Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris Journal of Investigative Dermatology · 2017 · 71 citations