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    Glossary N-Acetylcysteine

    supplement that replenishes antioxidant glutathione and supports detoxification

    N-Acetylcysteine (NAC) is a supplement and medication derived from the amino acid L-cysteine. It is commonly used to help replenish levels of the antioxidant glutathione in the body, support liver detoxification, and treat conditions like acetaminophen overdose and chronic respiratory issues. NAC has also been studied for its potential benefits in promoting hair growth and treating certain types of alopecia due to its antioxidant properties.

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    1. N-acetylcysteine in the treatment of trichotillomania International Journal of Trichology · 2012 · 65 citations
    2. Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome Molecular Human Reproduction · 2021 · 53 citations
    3. Trichotillomania: a good response to treatment with N-acetylcysteine Anais Brasileiros de Dermatologia · 2017 · 27 citations
    4. Trichotillomania treated with n-acetylcysteine Psychiatry and Clinical Psychopharmacology · 2018 · 3 citations
    5. Comparison of metformin and N-acetylcysteine on metabolic parameters in women with polycystic ovarian syndrome International journal of reproduction, contraception, obstetrics and gynecology · 2017 · 1 citations
    6. Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study Histochemistry and cell biology · 2024
    7. A case of trichotillomania with bulimia: combined with N-acetylcysteine synergistic therapy Research Square (Research Square) · 2021
    8. Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men QJM: An International Journal of Medicine · 2021
    9. Into the redox control: N-acetyl-cysteine pleiotropic effects from the laboratory to clinical applications Acupuncture and related therapies · 2013 · 4 citations
    10. Comparison of N-acetyl cysteine with metformin on clinical profile in anovulatory infertile women with PCOS International journal of clinical obstetrics and gynaecology · 2018
    11. TRAIL sensitization of PC3 prostate cancer cells by doxorubicin can be blocked by the anti-oxidant N-acetyl-cysteine or by the iron chelator deferoxamine Clinical Cancer Research · 2006
    12. Treatment with ImuVert/JV-Acetylcysteine Protects Rats from Cyclophosphamide/ Cytarabine-Induced Alopecia Cancer investigation · 1992 · 26 citations
    13. Evidence of hair loss after subacute exposure to 2-chloroethyl ethyl sulfide, a mustard analog, and beneficial effects ofN-acetyl cysteine Journal of Biochemical and Molecular Toxicology · 2004 · 14 citations
    14. Influence of <i>FHIT</i> on benzo[ <i>a</i> ]pyrene-induced tumors and alopecia in mice: Chemoprevention by budesonide and <i>N</i> -acetylcysteine Proceedings of the National Academy of Sciences of the United States of America · 2006 · 24 citations
    15. Trichotillomania American Journal of Psychiatry · 2016 · 219 citations
    16. Effects of the Usage of l-Cysteine (l-Cys) on Human Health 2018 · 75 citations
    17. Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing International Journal of Molecular Sciences · 2022 · 68 citations
    18. Psychocutaneous disease Journal of The American Academy of Dermatology · 2017 · 38 citations
    19. Treatment options for alopecia: an update, looking to the future Expert Opinion on Pharmacotherapy · 2012 · 35 citations
    20. Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods Dermatology and Therapy · 2018 · 30 citations
    21. Recent advances in the treatment of trichotillomania (hair‐pulling disorder) Dermatologic Therapy · 2020 · 24 citations
    22. Management of the psychological comorbidities of dermatological conditions: practitioners&#39; guidelines Clinical, Cosmetic and Investigational Dermatology · 2017 · 23 citations
    23. Trichotillomania: a case report with clinical and dermatoscopic differential diagnosis with alopecia areata 2017 · 14 citations
    24. Monilethrix: A rare hereditary condition Indian Journal of Dermatology · 2013 · 12 citations
    25. Recent advances in congenital ichthyoses 2015 · 10 citations
    26. Trichotillomania: What Do We Know So Far? Skin appendage disorders · 2021 · 8 citations
    27. Polycystic Ovary Syndrome and Oxidative Stress—From Bench to Bedside International journal of molecular sciences · 2023 · 6 citations
    28. A Systematic Review and Bayesian Network Meta-Analysis of Medical Therapies for Lichen Planopilaris Dermatology · 2023 · 4 citations
    29. Dissecting hair breakage in alopecia areata: the central role of dysregulated cysteine homeostasis Amino Acids · 2024 · 3 citations
    30. Trichotillomania – therapeutic possibilities Journal of Education, Health and Sport · 2023 · 2 citations