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This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.

This study found that in mice, Bacillus anthracis infections destroy hair follicles by progressing inward from the surface and clear when inflammatory cells disperse the bacteria after 3-4 days.

This study found that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by affecting the linoleic acid metabolism-Mg2+ pathway in a sodium sulfide-induced mouse model, highlighting new insights for clinical diagnosis and treatment strategies.

This study revealed that tofacitinib may inhibit CD8⁺ T cell infiltration in alopecia areata by modulating the linoleic acid metabolism-Mg²⁺ pathway, providing new insights for potential treatments and diagnosis.

This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.

In this study, researchers found that in mice, gonadal hormones and biological sex do not affect the expression of SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in the respiratory tract, regardless of disease state.

This study concluded that ablative fractional lasers may induce hair regrowth in mice by activating the Wnt/β-catenin pathway.

This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.

This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.

This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.

Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.

This study found that folic acid deficiency in infant mice moderately worsened rotaviral disease, while zinc deficiency did not significantly affect rotaviral disease progression.

This study found that finasteride and luteolin may prevent hair loss and promote hair growth in vitro and in vivo by modulating specific gene expressions related to cell differentiation and apoptosis.

This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.

This study found that exosomes derived from hypoxia-conditioned mesenchymal stem cells modulated inflammatory biomarkers by decreasing CXCL12 and increasing IL-10 expression in a DHT-induced androgenic alopecia mouse model, indicating potential for treating hair loss through immunoregulation.

This study introduced and validated a reliable and reproducible metal-free mouse model for ACLR surgery, providing a new tool to investigate the molecular mechanisms of graft-tunnel healing.

This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.

The reinforced collagen sponge helps grow normal hair in mice.

In this study, single-cell sequencing revealed clonal expansions of CD4+ and CD8+ T cells in murine and human alopecia areata, supporting the development of predictive models for human disease.

In this study, researchers discovered that the HrasG12V oncogenic mutation in murine skin epithelial cells initially promotes progenitor cell renewal but later leads to a balanced differentiation, stabilizing clone growth.

Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.

In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.

In this study, researchers observed that oncogenic HrasG12V in single murine epidermal cells leads to an initial increase in progenitor cell renewal, but ultimately results in balanced cell fate choices that limit clone growth.

This review discusses the biology of hair follicle stem cells and highlights their potential for applications in regenerative medicine, drug, and gene delivery, but reports no new clinical results.

This review examines the use of exosomes in skin rejuvenation and hair regeneration but reports no new clinical results, noting challenges in purification and practical use for clinical applications.

This study found that rete ridge morphogenesis in mammalian skin is directed by a BMP-dependent developmental program, which is evolutionarily distinct from other known pathways controlling the development of hair follicles, sweat glands, and fingerprint ridges.

This literature review reported that fractional lasers, like the 1550-nm nonablative erbium-glass laser, may enhance hair regrowth by stimulating a wound healing process, but more randomized controlled trials are needed to confirm their effectiveness and optimize treatment parameters.

Hair follicle stem cells help maintain skin health after injury.