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This study highlights the need for standardized preclinical murine models to improve the translation of wound healing research to human clinical applications, specifically noting variations in diabetes duration, animal sex, and assessment methods on healing outcomes in rat models.

This study observed that aberrant DNA methylation in murine and human cutaneous squamous cell carcinoma likely contributes to the silencing of tumor suppressor genes, notably affecting the FILIP1L gene.

This study found that applying dexamethasone to mice induced catagen-like follicle changes significantly earlier and more consistently than a vehicle, such changes being useful for studying hair follicle regression.

In this study, neonatal murine skin-derived cells transplanted using a mini-chamber method successfully produced robust and normal hair, contrasting with human scalp follicles which did not achieve follicle reconstruction.

This study found that OR-101, a selective JAK3/TEK inhibitor, was associated with dose-dependent improvements in hair growth in humanized mice with alopecia areata, suggesting its potential as a treatment option.

This study characterized the inflammatory response in a murine burn model, revealing similarities to human burns and supporting the model's use in testing therapies for burn complications.

In this study involving a murine skin infection model, researchers found that the Trichophyton mentagrophytes strain TIMM 2789, specific to rodents, induced typical symptoms of superficial dermatophytosis, while revealing that the fungal gene SUB6 is not essential for virulence.

In this study, researchers used a mouse model of alopecia areata to demonstrate that both ruxolitinib and baricitinib, oral JAK inhibitors, reduced hair loss, CD8+ cell infiltration, and expression of disease-related markers, with baricitinib showing greater effectiveness.

This study in a murine model of alopecia areata found that IFNg is crucial while perforin is not necessary for CD8 T cell-mediated disease development.

In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.

This study established a murine chronic graft-versus-host disease model with scleroderma features, showing typical skin changes and cellular infiltrates associated with the condition.

This study developed a validated murine model of hypertrophic scar contraction, demonstrating similarities to human skin and observing graft contraction and tissue characteristics over time.

This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.

In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.

In this study, researchers found that the absence of P-selectin delays inflammatory cell recruitment and reepithelialization in fetal wounds, although scar formation still occurs in later gestation wounds.

This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.

OR101 may effectively treat atopic dermatitis and similar skin conditions.

This study investigated alopecia areata in a mouse model, finding that tofacitinib may inhibit disease progression by modulating linoleic acid metabolism and magnesium pathways, particularly affecting CD8+ T cell infiltration in hair follicles, offering insights for potential treatments.

This study suggests that local skin inflammation may enhance the deposition of autoantibodies in the skin, potentially affecting the severity of pemphigus lesions in mice.

The researchers reported that in a mouse model of alopecia areata, tofacitinib treatment influenced disease progression by modulating CD8⁺ T cell infiltration through the linoleic acid metabolism and magnesium ion pathway, offering insights into potential treatment approaches.

This study found that in a mouse model of alopecia areata, tofacitinib inhibited CD8+ T cell infiltration at hair follicles by modulating linoleic acid metabolism and magnesium pathways, offering insights into potential therapeutic strategies for the condition.

In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.

This study found that applying low-intensity ultrasound enhanced hair growth on the treated area of mice with androgenic alopecia, potentially by affecting the action of finasteride.

This study evaluated an herbal emulgel formulation containing extracts from Wedelia chinensis and Cassytha filiformis for hair growth promotion in rats, finding that the combined formulation significantly increased hair growth compared to both individual extracts and the control group.

This study found that variations in mouse skin thickness, influenced by gender and hair growth cycles, significantly affect optical scattering measurements, which are important for developing biomedical optics techniques.

This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.

Enhancing Tregs can protect against alopecia areata.

In this study, intrathecal progesterone administration initially worsened mechanical allodynia in mice after nerve injury, but later reduced pain when applied during the maintenance phase, highlighting distinct roles for cytochrome P450c17 and 5α-reductase in neuropathic pain modulation.

This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.

This study found that FLASH radiation within a Spread-out Bragg Peak retained its normal tissue-sparing effect compared to conventional radiation, with a 40% reduction in acute skin damage and an 18% reduction in fibrotic development in mice.