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This study found that the multifunctional exosome-based delivery platform EX104 reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, performing comparably to minoxidil while also enhancing capillary growth and follicular proliferation.

In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

This study found that inhibiting NF-κB Essential Modulator (NEMO) in senescent murine dermal fibroblasts successfully reduced key factors associated with the senescence associated secretory phenotype (SASP), highlighting its potential as a therapeutic target for aging-related diseases.

This study evaluated an AI-driven system for personalizing non-medicated hair loss treatments in women, showing significant improvements in hair growth, shedding, texture, and scalp health over 24 weeks, with no adverse effects reported.

This study found that human hair follicle-derived mesenchymal stem cells demonstrated enhanced wound healing capabilities compared to umbilical cord-derived stem cells in laboratory and animal models.

This study reported that a self-pumping organohydrogel dressing equipped with hydrophilic fractal microchannels significantly increased exudate drainage efficiency and enhanced burn wound healing in mice, reducing dermal cavity size and accelerating blood vessel and hair follicle regeneration compared to commercial dressings.

This study established a murine model for radiation-induced skin reactions, replicating clinical and histological features to aid future mechanistic and therapeutic research.

This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.

The authors developed a severe mouse model of chronic graft-versus-host disease and reported that rapamycin treatment improved survival compared to placebo, potentially by promoting regulatory T cell expansion.

This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.

This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.

This study found that an imbalance of selenium in a C57BL/6 mouse model led to hair loss with color change and was linked with changes in hair follicle apoptosis markers.

In this murine study, researchers found that topical treatment with Philippine stingless bee propolis increased folliculogenesis, epidermal thickness, and melanogenesis, but not hair length, potentially supporting hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia models.

In this study, researchers found that cyclophosphamide treatment unexpectedly reduced splenic melanin deposition in a murine model, whereas this effect was down-regulated more by the normal and dystrophic catagen phase of the hair cycle.

In this study, engineered skin substitutes containing murine dermal papilla cells developed hair follicle-like structures when grafted onto mice, suggesting a model for generating chimeric hair.

In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.

This study found that persistent activation of Wnt signaling in mouse models leads to cyst formation in hair follicles, resembling acne, and that these cysts can be partially reduced by certain acne treatments.

In this study, researchers found that hair follicles and dermal fibroblasts, including dermal papilla cells, supported sustained hair growth in transplanted murine models, with RNA-seq analysis revealing active signaling pathways and gene expression patterns.

In this study, researchers identified that upon tissue injury in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state with SOX11 and SOX4 playing a central role in modulating epidermal development and cell migration genes.

This study found that the antiviral drug daclatasvir significantly improved fibrosis and quality of life in a mouse model of recessive dystrophic epidermolysis bullosa, suggesting potential for treating this and other fibrotic diseases.

This study found that topical application of the BRAF inhibitor vemurafenib improved wound healing and promoted hair follicle regeneration in a diabetic murine model.

This study found that HB-EGF and TGF-α work together to stimulate wound healing in a murine model of thermal injury, with peak keratinocyte proliferation observed by postburn day five.

This study found that electrospun membranes with aligned surface topography enhanced wound healing and hair follicle regeneration while modulating the immune response in a mouse skin wound model.

In this study, treatment with IL-2C to expand Tregs effectively halted hair loss progression in a murine model of alopecia areata.

This study found that NIMP-R14-conjugated nanoparticles, loaded with roflumilast, effectively targeted neutrophils to reduce inflammation and improve symptoms in a mouse model of psoriasiform dermatitis, suggesting potential for targeted therapy in autoimmune skin diseases.

In this study, PRP-derived exosomes significantly outperformed minoxidil in promoting hair regeneration in a murine model of androgenetic alopecia, with the combination of both treatments showing enhanced follicular regeneration and increased markers of tissue proliferation and Wnt signaling pathway activity.

This study found that hypoxia-conditioned mesenchymal stem cell exosomes increased GM-CSF and decreased IL-1 expression in a dose-dependent manner in a murine model, suggesting potential for treating androgenetic alopecia.

Murine cytomegalovirus does not cause alopecia areata in these mice.

This study found that proteolytic activities in murine skin vary with hair cycle stages, with significant collagenase activity during the early anagen phase.