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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Doctors need to be better prepared to assess and treat obesity in patients.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.

A blood pressure drug, diltiazem, may also help treat influenza.

Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

Aggressive scalp squamous cell carcinomas have a high death rate and need early, strong treatment.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

The AndroCoV Clinical Scoring is a quick, accurate, and free tool for diagnosing COVID-19.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

Finasteride does not prevent bladder cancer.