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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Certain hormone treatments can improve acne and related conditions in women.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.

Photobiomodulation may help with hair growth and wound healing, but research is inconsistent and needs better quality studies.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Most skin changes during pregnancy go away after giving birth.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.