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    Glossary Mitochondrial DNA

    genetic material in mitochondria inherited only from the mother

    Mitochondrial DNA (mtDNA) is the genetic material found in mitochondria, the energy-producing structures within cells. Unlike the DNA in the cell nucleus, mtDNA is inherited solely from the mother and is used to study maternal lineage and certain genetic disorders.

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    1. Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice Free radical biology & medicine · 2014 · 53 citations
    2. Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner Cell Death & Differentiation · 2016 · 42 citations
    3. Molecular–clinical correlations in a family with variable tissue mitochondrial DNA T8993G mutant load Molecular genetics and metabolism · 2006 · 35 citations
    4. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers Environmental and Molecular Mutagenesis · 2002 · 12 citations
    5. Mitochondrial DNA Damage, Oxidative Stress, and Atherosclerosis Circulation · 2013 · 12 citations
    6. Mitochondrial DNA 10158T>C mutation in a patient with mitochondrial encephalomyopathy with lactic acidosis, and stroke-like episodes syndrome Medicine · 2020 · 5 citations
    7. Effects of Hair dyes on Sequence Analysis of Hair Mitochondrial DNA Hypervariable Region 1 Journal of Biotechnology Research Center · 2017 · 2 citations
    8. Mitochondrial DNA Variation in Human Hair Shafts Influenced by Physical Characteristics: A Massively Parallel Sequencing Analysis Genes · 2026
    9. The mutational analysis of mitochondrial DNA in maternal inheritance of polycystic ovarian syndrome Frontiers in Endocrinology · 2023
    10. Fidelity of the Human Mitochondrial DNA Polymerase Journal of Biological Chemistry · 2006 · 101 citations
    11. Quantitation of human mitochondrial DNA and whole mtGenomes sequencing of fingernail/hair shaft samples Forensic Sciences Research · 2024 · 3 citations
    12. The legacy of Bruce Ames and mitochondrial DNA mutagenicity: integrating oxidative stress, aging, and modern perspectives Frontiers in Molecular Biosciences · 2025
    13. Antiretroviral nucleoside and nucleotide analogues and mitochondria AIDS · 2004 · 138 citations
    14. Resistance of degraded hair shafts to contaminant DNA Forensic Science International · 2005 · 69 citations
    15. Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor Scientific reports · 2020 · 3 citations
    16. Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying Cell Regeneration · 2025
    17. Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature International journal of molecular sciences · 2024
    18. Mitochondrial dysfunction as a cause of ageing Journal of Internal Medicine · 2008 · 384 citations
    19. Photosensitized 2-amino-3-hydroxypyridine-induced mitochondrial apoptosis via Smac/DIABLO in human skin cells Toxicology and applied pharmacology · 2016 · 10 citations
    20. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009 · 53 citations
    21. Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update Mechanisms of Ageing and Development · 2018 · 19 citations
    22. Stem cell identification-<i>in vivo</i> lineage analysis versus <i>in vitro</i> isolation and clonal expansion The Journal of Pathology · 2012 · 17 citations
    23. Association of mtDNA M/N haplogroups with systemic lupus erythematosus: a case-control study of Han Chinese women Scientific Reports · 2015 · 11 citations
    24. The crosstalk between PTEN ‐induced kinase 1‐mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata Experimental Dermatology · 2023 · 6 citations
    25. The Charnoly body as a universal biomarker of cell injury Biomarkers and Genomic Medicine · 2014 · 6 citations
    26. THE HUMAN HAIR FOLLICLE AS SENTINEL FOR DRUGS EVALUATION: DEMONSTRATION OF TETRACYCLINE ADHESION TO HAIR FOLLICLE AS PROPOSED MECHANISM IN DYSFUNCTIONAL HAIR LOSS International journal of research - granthaalayah · 2020 · 4 citations
    27. TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells Cell Death and Disease · 2024
    28. Dual deficiency of melatonin and dihydrotestosterone promotes stromal cell damage and mediates prostatitis via the cGAS-STING pathway in sleep-deprived mice Cell communication and signaling · 2024
    29. TLR9 activation in large wound induces tissue repair and hair follicle regeneration via gamma delta T cells bioRxiv (Cold Spring Harbor Laboratory) · 2024
    30. Issue Information Clinical and Experimental Dermatology · 2017