Search
for

    Glossary Mitochondria

    organelles generating energy for cellular functions

    Mitochondria, often referred to as the "powerhouses of the cell," are organelles found in the cytoplasm of eukaryotic cells. They generate most of the cell's supply of adenosine triphosphate (ATP), which is used as a source of chemical energy. Mitochondria also play a role in other cellular processes such as signaling, cellular differentiation, and cell death, as well as maintaining control of the cell cycle and cell growth.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Mitochondrial dysfunction as a cause of ageing Journal of Internal Medicine · 2008 · 384 citations
    2. Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review Antioxidants · 2018 · 280 citations
    3. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013 · 277 citations
    4. Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization Cell Metabolism · 2014 · 222 citations
    5. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients Molecular psychiatry · 2013 · 198 citations
    6. Antiretroviral nucleoside and nucleotide analogues and mitochondria AIDS · 2004 · 138 citations
    7. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity The Journal of Cell Biology · 2015 · 98 citations
    8. Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles Journal of Investigative Dermatology · 2013 · 95 citations
    9. Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN Journal of the National Cancer Institute · 2012 · 81 citations
    10. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting Journal of biomedical science · 2015 · 76 citations
    11. Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1 Aging · 2017 · 75 citations
    12. Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function Cell death and disease · 2018 · 74 citations
    13. Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver Scientific reports · 2017 · 59 citations
    14. Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions Journal of Investigative Dermatology · 2015 · 56 citations
    15. Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice Free radical biology & medicine · 2014 · 53 citations
    16. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism Journal of Lipid Research · 2018 · 45 citations
    17. Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner Cell Death & Differentiation · 2016 · 42 citations
    18. Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire 2017 · 40 citations
    19. Molecular–clinical correlations in a family with variable tissue mitochondrial DNA T8993G mutant load Molecular genetics and metabolism · 2006 · 35 citations
    20. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss Journal of Medicinal Chemistry · 2021 · 33 citations
    21. Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis Acta neuropathologica communications · 2019 · 29 citations
    22. Minoxidil opens mitochondrial K<sub>ATP</sub> channels and confers cardioprotection British Journal of Pharmacology · 2004 · 28 citations
    23. Platelets Facilitate Wound Healing by Mitochondrial Transfer and Reducing Oxidative Stress in Endothelial Cells Oxidative Medicine and Cellular Longevity · 2023 · 27 citations
    24. PKC downregulation upon rapamycin treatment attenuates mitochondrial disease Nature metabolism · 2020 · 26 citations
    25. Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-β and mitochondrial signaling pathway. PubMed · 2018 · 24 citations
    26. Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK Journal of Neurochemistry · 2008 · 22 citations
    27. Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium Journal of Investigative Dermatology · 2018 · 17 citations
    28. Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts Journal of Biomedical Science · 2022 · 14 citations
    29. A Connection between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis Journal of proteome research · 2008 · 14 citations
    30. Copper Modulates Mitochondrial Oxidative Phosphorylation to Enhance Dermal Papilla Cells Proliferation in Rex Rabbits International Journal of Molecular Sciences · 2022 · 12 citations