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    Did you mean MicroRNAs?
    Glossary MicroRNAs

    MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in regulating gene expression by binding to messenger RNAs (mRNAs) and inhibiting their translation or promoting their degradation. In the context of hair loss and hair biology, miRNAs are involved in various processes such as hair follicle development, cycling, and the response to stressors that can lead to conditions like androgenetic alopecia. Key distinguishing characteristics of miRNAs include their ability to modulate multiple target genes simultaneously, which can influence cellular pathways related to hair growth and loss. Understanding the role of miRNAs in hair biology may offer insights into potential therapeutic targets for hair loss treatments.

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    1. MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives Frontiers in Cell and Developmental Biology · 2026
    2. MicroRNA control of signal transduction Nature Reviews Molecular Cell Biology · 2010 · 1066 citations
    3. MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2 Stem cells · 2012 · 123 citations
    4. MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway Journal of Cell Biology · 2014 · 103 citations
    5. Importance of microRNAs in skin morphogenesis and diseases. PubMed · 2008 · 70 citations
    6. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration Cell Cycle · 2012 · 56 citations
    7. MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes The Journal of Clinical Endocrinology and Metabolism · 2016 · 50 citations
    8. Control by a hair’s breadth: the role of microRNAs in the skin Cellular and Molecular Life Sciences · 2012 · 41 citations
    9. MicroRNAs in skin tissue engineering Advanced drug delivery reviews · 2015 · 39 citations
    10. Identification of microRNAs in Wool Follicles during Anagen, Catagen, and Telogen Phases in Tibetan Sheep PLoS ONE · 2013 · 37 citations
    11. High-throughput sequencing of hair follicle development-related micrornas in cashmere goat at various fetal periods Saudi Journal of Biological Sciences · 2017 · 33 citations
    12. MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment Molecular diagnosis & therapy · 2017 · 32 citations
    13. MicroRNAs in the skin: role in development, homoeostasis and regeneration Clinical Science · 2017 · 31 citations
    14. MicroRNA-Enriched Exosomes from Different Sources of Mesenchymal Stem Cells Can Differentially Modulate Functions of Immune Cells and Neurogenesis Biomedicines · 2021 · 29 citations
    15. Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method British Journal of Dermatology · 2011 · 29 citations
    16. MicroRNA in skin diseases European Journal of Dermatology · 2017 · 27 citations
    17. Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells Biological Research · 2014 · 25 citations
    18. Current insight into the functions of microRNAs in common human hair loss disorders: a mini review Human Cell · 2021 · 22 citations
    19. An Integrated Analysis of MicroRNA and mRNA Expression Profiles to Identify RNA Expression Signatures in Lambskin Hair Follicles in Hu Sheep PLoS ONE · 2016 · 22 citations
    20. Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone Molecular Medicine Reports · 2012 · 22 citations
    21. MicroRNAs take part in pathophysiology and pathogenesis of Male Pattern Baldness Molecular Biology Reports · 2009 · 21 citations
    22. Identification of ultraviolet B radiation-induced microRNAs in normal human dermal papilla cells Molecular Medicine Reports · 2014 · 18 citations
    23. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging Journal of Investigative Dermatology · 2019 · 16 citations
    24. Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells Annals of Dermatology · 2016 · 16 citations
    25. Identification of blood microRNA alterations in patients with severe active alopecia areata Journal of Cellular Biochemistry · 2019 · 15 citations
    26. Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats Functional & Integrative Genomics · 2022 · 14 citations
    27. The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat Scientific Reports · 2018 · 13 citations
    28. Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients Journal of Dermatological Science · 2020 · 12 citations
    29. EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression Aging · 2020 · 12 citations
    30. Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells Molecular Medicine Reports · 2015 · 12 citations