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    Did you mean DNA Methyltransferase 1?
    Glossary DNA Methyltransferase 1

    maintains DNA methylation patterns during cell division

    DNA Methyltransferase 1 (DNMT1) is an enzyme that plays a crucial role in maintaining DNA methylation patterns during cell division. It adds methyl groups to the cytosine bases of DNA, which can regulate gene expression by turning genes on or off. This process is essential for normal development, genomic stability, and cellular differentiation.

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    Research 30 of 459

    1. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012 · 72 citations
    2. OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases Stem Cell Research & Therapy · 2019 · 57 citations
    3. DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen in Combination with 4% Niacinamide, 0.05% Retinoic Acid, or Placebo BioMed Research International · 2019 · 20 citations
    4. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012 · 1 citations
    5. 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis Journal of Investigative Dermatology · 2018
    6. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Genes & Development · 2008 · 667 citations
    7. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    8. Anagen effluvium due to azathioprine in a patient with normal thiopurine S-methyltransferase levels: A videodermoscopic analysis International journal of dermatology and venereology · 2022
    9. Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development Developmental biology · 2021 · 6 citations
    10. DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018 · 1 citations
    11. EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair Genes & Development · 2011 · 354 citations
    12. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    13. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    14. Hypothalamic DNA methylation in rats with dihydrotestosterone‐induced polycystic ovary syndrome: effects of low‐frequency electro‐acupuncture Experimental physiology · 2018 · 18 citations
    15. Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice Journal of Tissue Engineering and Regenerative Medicine · 2022 · 6 citations
    16. Epigenetic regulations on skin wound healing: implications from current researches. PubMed · 2015 · 5 citations
    17. Non-histone Methylation of SET7/9 and its Biological Functions Recent patents on anti-cancer drug discovery · 2021 · 3 citations
    18. 0843 N6-methyladenosine RNA modification promotes keratinocyte proliferation and cutaneous wound repair through regulation of MTOR stability Journal of Investigative Dermatology · 2025 · 1 citations
    19. H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers Nature Communications · 2026
    20. Epigenetic Modulation of ESR1 and DNMT3A Following Finasteride Exposure: Implications for Female Reproductive Function Physiology · 2026
    21. ASH2L mediates epidermal differentiation and hair follicle morphogenesis via H3K4me3 modification 2024
    22. Serotoninergic and melatoninergic systems are fully expressed in human skin ˜The œFASEB journal · 2002 · 249 citations
    23. Study on Histamine Related Enzyme Activities during Murine Hair Cycle. EXPERIMENTAL ANIMALS · 1997 · 4 citations
    24. Attenzione divisa nei pazienti con cerebrolesione acquisita Journal of Medicinal Chemistry · 2008
    25. Finasteride inhibits epinephrine synthesis in humans: implication for sexual dysfunction Endocrine Abstracts · 2022
    26. Author response: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ 2017
    27. METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α Cell Death and Disease · 2025 · 3 citations
    28. Identification and Characterization of Two Se6OMTs from Stephania epigaea Offer Novel Insights into the Biosynthetic Pathway of Cepharanthine Metabolites · 2025 · 3 citations
    29. The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus Journal of Dermatological Science · 2008 · 6 citations
    30. Pathophysiological mechanisms implicated in postpartum depression Frontiers in Neuroendocrinology · 2019 · 142 citations