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Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Some skin diseases and their treatments can negatively affect male fertility.

Higher androgen levels might make COVID-19 worse, especially in men.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Hair amino acid levels can indicate metabolic disorders.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

The document discusses new insights into how hormones affect male sexual health and related conditions.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Women with Polycystic Ovary Syndrome have higher levels of the hormone ghrelin, which may be linked to the cause of the condition.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Eating plant-based anti-inflammatories and antioxidants may help manage long-term COVID-19 health issues.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.

Steroid-binding globulins have important roles beyond just transporting steroids.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.