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    Did you mean Marie Unna Hereditary Hypotrichosis?
    Glossary Marie Unna Hereditary Hypotrichosis

    rare genetic disorder causing sparse or absent hair growth

    Marie Unna Hereditary Hypotrichosis (MUHH) is a rare genetic disorder characterized by abnormal hair growth, leading to sparse or absent hair on the scalp and other parts of the body. It is inherited in an autosomal dominant pattern, meaning only one copy of the altered gene is necessary for the condition to manifest.

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    1. Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis Nature Genetics · 2009 · 181 citations
    2. A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family British Journal of Dermatology · 2000 · 36 citations
    3. Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a <i>U2HR</i> mutation American Journal of Medical Genetics - Part A · 2010 · 11 citations
    4. Marie-unna hereditary hypotrichosis International Journal of Trichology · 2014 · 4 citations
    5. Marie Unna Hereditary Hypotrichosis Gene Maps to Human Chromosome 8p21 Near Hairless Journal of Investigative Dermatology · 2000 · 29 citations
    6. A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis Mammalian genome · 2009 · 21 citations
    7. Marie Unna hereditary hypotrichosis: Identification of a U2HR mutation in the family from the original 1925 report Journal of the American Academy of Dermatology · 2011 · 14 citations
    8. Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript Experimental Dermatology · 2010 · 14 citations
    9. Marie‐Unna Hereditary Hypotrichosis: Case Report and Review of the Literature Pediatric dermatology · 2011 · 12 citations
    10. Identification of a novel heterozygous mutation in the first Japanese case of Marie Unna hereditary hypotrichosis The Journal of Dermatology · 2013 · 6 citations
    11. A newly identified missense mutation of the HR gene is associated with a novel, unusual phenotype of Marie Unna Hereditary Hypotrichosis 1 including limb deformities Archives of Dermatological Research · 2012 · 6 citations
    12. Marie Unna Hereditary Hypotrichosis Gene Maps to Human Chromosome 8p21 Near Hairless Journal of Investigative Dermatology · 2000 · 4 citations
    13. Marie‐Unna Hereditary Hypotrichosis or Autosomal Recessive Hereditary Hypotrichosis with Woolly Hair: The Diagnostic Dilemma of Labeling Cases with Hypotrichosis Pediatric dermatology · 2011 · 2 citations
    14. Significant Hair Regrowth With 5% Topical Minoxidil in a Child With Marie Unna Hereditary Hypotrichosis Caused by a Recurrent <i>HRURF</i> Variant Journal of Cosmetic Dermatology · 2025
    15. Clinical course of the first Japanese family with Marie Unna hereditary hypotrichosis: a follow-up report European Journal of Dermatology · 2018
    16. Marie‐Unna Hereditary Hypotrichosis: Case Report and Review of the Literature Pediatric dermatology · 2011
    17. [Congenital hereditary hypotrychosis. Generalized autosomal dominant hypotrichosis with pili torti (hypotrichosis congenita hereditaria Marie Unna)]. PubMed · 1979 · 5 citations
    18. Hypotrichosis congenita of Marie Unna European Journal of Dermatology · 2001
    19. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    20. The genetics of hair shaft disorders Journal of The American Academy of Dermatology · 2008 · 59 citations
    21. Office Diagnosis of Hair Shaft Defects Seminars in cutaneous medicine and surgery · 2006 · 33 citations
    22. Hair physiology and its disorders Drug Discovery Today: Disease Mechanisms · 2008 · 31 citations
    23. Differential diagnosis of hair loss in children. Differentialdiagnose des Haarausfalls bei Kindern Journal der Deutschen Dermatologischen Gesellschaft · 2004 · 30 citations
    24. Molecular Basis of Hereditary Hair Diseases The Keio Journal of Medicine · 2023
    25. Recalcitrant Female Pattern Hair Loss Like Alopecia Unveils Unexpected Rare Entity Clinical Cosmetic and Investigational Dermatology · 2025
    26. Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA 2018 · 3 citations
    27. Two females with hair loss Journal der Deutschen Dermatologischen Gesellschaft · 2019
    28. Odd-Looking Hair and Progressive Alopecia in Mother and Son JAMA Dermatology · 2014
    29. Clinical and molecular genetic studies in hereditary hair loss 2021
    30. Polarized microscopy in genetic hair disorders: case series 2025