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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

The Rotterdam Study aims to understand various diseases in older adults.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Bald men are often viewed more negatively and as older than they really are.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.

The document concludes that hair transplantation is recommended for those not helped by medical treatments, but warns that high-density transplants may lower hair survival rates.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.

Minoxidil 1% and 2% best promote hair growth and may prevent hair loss.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

The document suggests using fat grafting and laser therapy to improve the aging Asian face and hair restoration techniques tailored to Asian hair characteristics, emphasizing natural results and cultural sensitivity.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

Modern wound dressings like hydrocolloids, alginates, and hydrogels improve healing and are cost-effective.