59 citations,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
58 citations,
March 2020 in “Scientific Reports” EGFR-TKIs can cause significant skin, nail, and organ side effects.
58 citations,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
[object Object] 58 citations,
April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
57 citations,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
56 citations,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
55 citations,
November 2004 in “Expert opinion on drug safety” Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.
54 citations,
October 2019 in “Cochrane library” Some drugs may reduce prostatitis symptoms short-term with few side effects.
53 citations,
February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
53 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
52 citations,
September 1996 in “Obstetrics & Gynecology” People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.
51 citations,
October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
51 citations,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
51 citations,
October 1980 in “The New England Journal of Medicine” Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
50 citations,
May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
49 citations,
July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
49 citations,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
48 citations,
September 2013 in “Oncologist” Endocrine therapies for cancer significantly increase the risk of hair loss.
48 citations,
November 1992 in “International Journal of Dermatology” Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
47 citations,
December 2020 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
45 citations,
January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
44 citations,
April 2015 in “PubMed” Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
44 citations,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
44 citations,
August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
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January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
41 citations,
September 2018 in “Australasian journal of dermatology” No systemic treatment for alopecia areata has strong evidence of effectiveness.
41 citations,
July 2002 in “Clinical and Experimental Dermatology” Effective hair loss assessment requires a mix of precise measurement methods.
41 citations,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
40 citations,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.