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50 citations, August 2017 in “Diabetologia”

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

50 citations, January 2016 in “The Journal of Clinical Endocrinology and Metabolism”

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

48 citations, February 2013 in “Molecular and Cellular Endocrinology”

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

46 citations, September 2016 in “Clinical, Cosmetic and Investigational Dermatology”

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

45 citations, February 2001 in “Joint bone spine”

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

42 citations, August 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

41 citations, April 2010 in “Gender Medicine”

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

40 citations, April 2008 in “European journal of endocrinology”

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

40 citations, January 2003 in “Gynecological Endocrinology”

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

38 citations, July 2012 in “international journal of endocrinology and metabolism”

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.