Search
for

    Did you mean Keratinocyte Stem Cells?
    Glossary Keratinocyte Stem Cells

    specialized skin cells that regenerate and form keratinocytes

    Keratinocyte Stem Cells (KSCs) are specialized cells found in the basal layer of the epidermis, the outermost layer of the skin. These cells have the unique ability to self-renew and differentiate into keratinocytes, which are the primary cells that make up the skin, hair, and nails. KSCs play a crucial role in skin regeneration and wound healing, making them essential for maintaining healthy skin and repairing damage.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells Journal of Dermatological Science · 2024 · 1 citations
    2. Transplantation of Keratinocyte Spore-Like Stem Cells Transplantation · 2012
    3. RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development Orphanet journal of rare diseases · 2022 · 5 citations
    4. Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells Nutrients · 2019 · 20 citations
    5. Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes Cell and Tissue Research · 1994 · 36 citations
    6. Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game? Experimental dermatology · 2012 · 11 citations
    7. l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase 2009 · 34 citations
    8. Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1 Cell Biology International · 2009 · 20 citations
    9. The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability Stem cells · 2013 · 28 citations
    10. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    11. Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model Frontiers in Medicine · 2025 · 8 citations
    12. Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment Stem cell research & therapy · 2021 · 14 citations
    13. Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field Experimental Dermatology · 2019 · 26 citations
    14. Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells Experimental Dermatology · 2012 · 6 citations
    15. Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales Scientific reports · 2022 · 5 citations
    16. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    17. Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis Nature Communications · 2011 · 36 citations
    18. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice EMBO molecular medicine · 2014 · 81 citations
    19. Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation Scientific Reports · 2017 · 27 citations
    20. Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model Journal of Microbiology and Biotechnology · 2024 · 3 citations
    21. Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy Stem Cell Research & Therapy · 2020 · 48 citations
    22. Rapid preparation of a noncultured skin cell suspension that promotes wound healing Cell and Tissue Banking · 2017 · 5 citations
    23. Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway Journal of Microbiology and Biotechnology · 2019 · 37 citations
    24. Effect of ethanol extract of plant mixture on hair regeneration in human dermal papilla cells and C57BL/6J mice Journal of Medicinal Plants Research · 2015 · 4 citations
    25. TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells Cell Death and Disease · 2024
    26. Beneficial effects of the conditioned medium of adipose tissue-derived stem cells on human follicular cells Seoul National University Open Repository (Seoul National University) · 2010
    27. Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration Biomaterials Research · 2024
    28. TLR9 activation in large wound induces tissue repair and hair follicle regeneration via gamma delta T cells bioRxiv (Cold Spring Harbor Laboratory) · 2024
    29. Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells 2010 · 77 citations
    30. Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice American Journal Of Pathology · 2008 · 55 citations