Search
for

    Did you mean Keratinocyte Stem Cells?
    Glossary Keratinocyte Stem Cells

    specialized skin cells that regenerate and form keratinocytes

    Keratinocyte Stem Cells (KSCs) are specialized cells found in the basal layer of the epidermis, the outermost layer of the skin. These cells have the unique ability to self-renew and differentiate into keratinocytes, which are the primary cells that make up the skin, hair, and nails. KSCs play a crucial role in skin regeneration and wound healing, making them essential for maintaining healthy skin and repairing damage.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Location and phenotype of human adult keratinocyte stem cells of the skin Differentiation · 2004 · 233 citations
    2. Vitamin D receptor is essential for normal keratinocyte stem cell function Proceedings of the National Academy of Sciences · 2007 · 143 citations
    3. Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage 2010 · 101 citations
    4. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    5. In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2005 · 52 citations
    6. Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying Journal of Investigative Dermatology · 2013 · 30 citations
    7. Keratinocyte stem cells of cornea, skin and hair follicles Elsevier eBooks · 1997 · 28 citations
    8. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    9. HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion Journal of Investigative Dermatology · 2017 · 25 citations
    10. WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation Journal of Investigative Dermatology · 2013 · 18 citations
    11. Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200 Journal of Investigative Dermatology · 2007 · 12 citations
    12. Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game? Experimental dermatology · 2012 · 11 citations
    13. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022 · 1 citations
    14. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research · 2012 · 1 citations
    15. From basic biology to engineered therapies: the keratinocyte stem cell playbook Frontiers in Medical Technology · 2026
    16. 557 Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth without affecting the characteristics of the stem cell population Journal of Investigative Dermatology · 2022
    17. Toxicological Responses in Keratinocyte Interfollicular Stem Cells 2018
    18. 876 Manipulation of stem cell divisional behavior: Selectively promoting asymmetric and symmetric keratinocyte divisions in vitro Journal of Investigative Dermatology · 2017
    19. Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice Cancer research · 2014
    20. Abstract 5216: Impact of Stat3 deletion or activation on keratinocyte stem/progenitor cells Cancer Research · 2012
    21. ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS DigtalCommons @ Texas Medical Center Library (Texas Medical Center) · 2012
    22. The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability Stem cells · 2013 · 28 citations
    23. SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling Journal of Investigative Dermatology · 2024 · 4 citations
    24. Transplantation of Keratinocyte Spore-Like Stem Cells Transplantation · 2012
    25. Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells Veterinary Dermatology · 2009 · 37 citations
    26. Continuous MEK inhibition by AZD6244 (ARRY-142886) results in exhaustion of the cutaneous keratinocytic stem cell pool and resembles senescence driven skin aging Journal of Clinical Oncology · 2008 · 2 citations
    27. In-vivo dedifferentiation of keratinocytes to epidermal stem cells The Lancet · 2002 · 1 citations
    28. Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes International journal of molecular sciences · 2023
    29. Implanted hair-follicle-associated pluripotent (HAP) stem cells differentiating to keratinocytes, macrophages and endothelial cells accelerated cutaneous wound closure and suppressed scar formation in a mouse model Research Square (Research Square) · 2022
    30. Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector Stem Cell Research & Therapy · 2013 · 18 citations