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    Did you mean Keratinocyte Differentiation?
    Glossary Keratinocyte Differentiation

    process where skin cells mature and produce protective keratin

    Keratinocyte differentiation, also known as keratinocyte maturation, is the process by which keratinocytes, the primary cells in the outer layer of the skin, develop and change as they move from the deeper layers to the surface. During this journey, they produce keratin, a protective protein, and eventually form the tough, outermost layer of the skin that acts as a barrier against environmental damage. This process is crucial for maintaining skin integrity and function.

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    1. Neutrophil gelatinase‐associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin Experimental dermatology · 2002 · 96 citations
    2. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    3. Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene <i>ID2</i>, by contact sensitizers in human bulge‐derived keratinocytes Journal of Biochemical and Molecular Toxicology · 2010 · 6 citations
    4. GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis Archives of Dermatological Research · 2013 · 24 citations
    5. Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation Experimental Cell Research · 1989 · 128 citations
    6. Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation International journal of oncology · 2009 · 8 citations
    7. Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels Bioengineering · 2022 · 1 citations
    8. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research · 2012 · 1 citations
    9. Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome International journal of molecular sciences · 2022 · 1 citations
    10. Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 2 citations
    11. Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles Scientific reports · 2022 · 1 citations
    12. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    13. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    14. 1617 Impact of type 2 cytokines on the keratinocytes-s. aureus interaction Journal of Investigative Dermatology · 2023
    15. Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs 2021 · 12 citations
    16. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    17. 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath 2019
    18. ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS DigtalCommons @ Texas Medical Center Library (Texas Medical Center) · 2012
    19. BMP2-mediated PTEN enhancement promotes differentiation of hair follicle stem cells by inducing autophagy Experimental cell research · 2019 · 24 citations
    20. Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes Experimental Dermatology · 2016 · 12 citations
    21. Proliferation and Differentiation of Human Hair Follicle Stem Cells on Chitosan-Skin Engineered Template in Vitro International Journal on Advanced Science, Engineering and Information Technology · 2017
    22. Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation 1986 · 23 citations
    23. Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation. The Journal of Cell Biology · 1994 · 104 citations
    24. Rancangan televisyen: Menyangga atau menyanggah bahasa dan budaya? PLoS ONE · 2004
    25. Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23 Journal of cosmetic dermatology · 2023
    26. LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy Journal of Investigative Dermatology · 2019
    27. LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion Journal of Investigative Dermatology · 2019
    28. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    29. Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard Experimental and Molecular Pathology · 2014 · 14 citations
    30. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations