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GlossaryKeratin Production

process by which skin cells create a protective protein

Keratin production refers to the process by which keratinocytes, specialized cells in the skin, hair, and nails, synthesize keratin, a fibrous structural protein. This protein provides strength and protection to these tissues, playing a crucial role in maintaining their integrity and resilience against physical and environmental damage.

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Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation

research Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation

18 citations, October 2018 in “Nutrients”

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

research Promoting Hair Growth and Hair Keratin Production with a Propolis Extract

July 2024 in “Journal of Investigative Dermatology”

Propolis extract can promote hair growth and increase keratin production.

research Exploring Natural Ways to Maintain Keratin Production in Hair Follicles

January 2024

Coconut and castor oils may naturally boost hair growth by increasing keratin.

research Endocrine Controls of Keratin Expression

54 citations, March 2009 in “BioEssays”

Hormones control keratin production in skin and hair.

research Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes

40 citations, July 2015 in “Journal of Cellular Biochemistry”

Cysteine helps maintain keratin production in skin cells even when iron is low.

research The Microanatomy, Cell Replication, and Keratin Gene Expression of Hair Follicles During a Photoperiod-Induced Growth Cycle in Sheep

20 citations, January 1995 in “Cells tissues organs”

Changing light periods synchronized wool growth cycles in sheep.

research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells

13 citations, December 2019 in “Nutrients”

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

research A Note on Postinflammatory Hair Darkening

9 citations, June 1959 in “Archives of dermatology”

Hair can darken after inflammation and then return to its original color.

A Prospective, Randomized Double-Blind, Placebo-Controlled Study for Safety and Efficacy of SesZen-Bio: A Proprietary Sesbania Grandiflora Extract in Managing Hair and Scalp Health in Healthy Adults

research A Prospective, Randomized Double-Blind, Placebo-Controlled Study for Safety and Efficacy of SesZen-Bio: A Proprietary Sesbania Grandiflora Extract in Managing Hair and Scalp Health in Healthy Adults

April 2024 in “International journal of clinical trials”

SesZen-Bio™ improves hair density, thickness, and overall hair health.

research Formulation and Evaluation of Polyherbal Hair Oil Containing Vitamin B7

June 2022 in “International Journal of Advanced Research in Science, Communication and Technology”

The polyherbal hair oil with Vitamin B7 may increase hair growth, reduce hair loss, and protect against dandruff.

Screening and Identification of LncRNAs Related to Villus Growth of Liaoning Cashmere Goats and Their Effects on Growth After FGF5 Treatment

research Screening and Identification of LncRNAs Related to Villus Growth of Liaoning Cashmere Goats and Their Effects on Growth After FGF5 Treatment

August 2019 in “Research Square (Research Square)”

Certain long non-coding RNAs in cashmere goats affect hair growth when treated with a specific growth factor.

research Identification of Key Genes and Signaling Pathways Related to Hetian Sheep Wool Density by RNA-Seq Technology

7 citations, May 2022 in “PLOS ONE”

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis

51 citations, July 2010 in “Trends in Endocrinology and Metabolism”

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation

research Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation

19 citations, November 2018 in “Nutrients”

Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.

research Follicular Ichthyosis: A Study of Four Patients with Congenital Follicular Hyperkeratosis

17 citations, July 1984 in “British journal of dermatology/British journal of dermatology, Supplement”

The four patients have a unique type of ichthyosis affecting hair follicles.

research Formulation and Examination of Organic Oil and Shampoo from Fish Scales

1 citations, December 2019 in “International journal of innovative technology and exploring engineering”

Fish scale-based organic hair oil and shampoo may improve hair health and prevent damage.

Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia

research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia

March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22

research Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22

52 citations, May 2015 in “PLOS Genetics”

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

research Is Thyrotropin-Releasing Hormone a Novel Neuroendocrine Modulator of Keratin Expression in Human Skin?

10 citations, February 2013 in “British Journal of Dermatology”

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

research Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism

7 citations, November 2022 in “Communications biology”

Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.

research Use of Rice Water (Oryza Sativa) and Hibiscus (Hibiscus Rosa-Sinensis)

June 2021 in “Journal of Emerging Technologies and Innovative Research”

Rice water and hibiscus can help improve hair health and growth.

research Aging of the Hair Follicle Pigmentation System

75 citations, January 2009 in “International journal of trichology”

Hair grays due to oxidative stress and fewer functioning melanocytes.

research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review

24 citations, January 2020 in “International Journal of Molecular Sciences”

Some plants with flavonoids may help treat hair loss and promote hair growth.

In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos

research In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos

6 citations, May 2022 in “Frontiers in physiology”

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.

research Healthy Hair: Form and Function

January 2015 in “Springer eBooks”

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

132 citations, January 2017 in “International Journal of Molecular Sciences”

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

research Annurca Apple Extract - A Breakthrough in Alopecia Phytotherapy: A Literature Review

February 2024 in “Archiv EuroMedica”

Annurca apple extract may help with hair growth and prevent hair loss.

Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla

research Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla

10 citations, July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.

research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

180 citations, January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D Receptor is crucial for normal skin and hair growth.

research Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia

5 citations, January 2021 in “Frontiers in Cell and Developmental Biology”

Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.