research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
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research Understanding Autoimmunity of Vitiligo and Alopecia Areata
Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis
Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.
research Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis
Applying 2% tofacitinib cream helped some children with severe hair loss grow back hair.
research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Treatment of Alopecia Areata in Pre-Adolescent Children with Oral Tofacitinib: A Retrospective Study
Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling
3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
research Combination Tofacitinib and Oral Minoxidil Treatment for Severe Alopecia Areata
Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
research Systematic Review and Quality Analysis of Studies on the Efficacy of Topical Diphenylcyclopropenone Treatment for Alopecia Areata
Topical DPCP is somewhat effective for hair loss in alopecia areata, but more research is needed.
research IL-12/IL-23 Neutralization Is Ineffective for Alopecia Areata in Mice and Humans
Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
research Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Areata: A Randomized Double-Blinded Parallel-Group Study
The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.
research Experience with Oral Tofacitinib in Severe Alopecia Areata with Different Clinical Responses
Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.
research Experience with Oral Tofacitinib in Adolescents and Adults with Alopecia Areata
Oral tofacitinib has a moderate success rate and is generally safe for treating hair loss in some patients.
research Case Report of Novel Combination of Anthralin and Calcipotriene Leading to Trichologic Response in Alopecia Areata
A new mix of anthralin and calcipotriene might help treat severe hair loss.
research Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review
Beard hair loss can signal early diabetes and thyroid issues, treatable with specific cream.
research Efficacy and Influence Factors of 308-nm Excimer Lamp with Minoxidil in the Treatment of Alopecia Areata
Using a 308-nm excimer lamp with minoxidil promotes hair growth in Alopecia Areata patients, especially younger ones or those with smaller bald spots.
research Gut Microbiome, Metabolome and Alopecia Areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Correlation Between Serum Granulysin Level and Clinical Activity in Patients with Alopecia Areata Before and After Tofacitinib Therapy
Higher granulysin levels in the blood are linked to more severe hair loss in alopecia areata patients, and these levels decrease after effective treatment.
research Frontal Fibrosing Alopecia Under Dynamic Optical Coherence Tomography
D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.
research Abrocitinib Improved Dupilumab-Resistant Severe Atopic Dermatitis with Comorbid Mild Alopecia Areata in a 12-Year-Old Boy: A Case Report with 1-Year Follow-Up
Abrocitinib effectively treated severe atopic dermatitis and mild alopecia areata in a 12-year-old boy after dupilumab failed.
research Oral Tofacitinib in Moderate and Severe Alopecia Areata: Case Series of 14 Patients
Tofacitinib helped regrow hair in most patients with severe hair loss.
research Editorial: Advances in Evaluation and Management of Hair Loss Disorders
Early diagnosis and personalized treatments are crucial for better hair loss management.
research Effects of the RV3466F Lotion on Female Telogen Effluvium: Results from a 16-Week, Multi-Centric, Controlled, Randomized Trial
RV3466F lotion significantly reduces hair loss and improves acute telogen effluvium.
research The Efficacy and Safety of Tofacitinib in Patients with Alopecia Totalis
Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Catalytic-Dependent and -Independent Activities of Polycomb Repressive Complex 1 Differentially Regulate Skin Stem Cell Specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research Understanding Cellular and Molecular Responses in the Treatment of Pediatric Lymphatic Anomalies
Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
research Defining the Molecular Signature of the Hair Follicle Dermal Sheath and Its Functional Requirement for Hair Cycle Progression During Catagen
The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
research Identification of Ferroptosis-Related Biomarkers in Alopecia Areata Through Machine Learning
Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.