June 2024 in “Dermatology and therapy” This study reviewed recent advancements in using botulinum toxin for treating androgenetic alopecia and emphasized the need for further research to determine the most effective injection sites and depths, as current strategies show inconsistent results.
1 citations
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July 2022 in “Dermatologic Therapy” This study found that a 6-week treatment with both brands of biotin and dexpanthenol significantly improved hair fall count and hair density in people with diffuse pattern hair loss, with no significant difference between the two brands.
This study observed that intramuscular injection of sodium 131iodide at doses of up to 1 mCi can successfully induce hypothyroidism in rats without significantly damaging muscle or nearby tissues, despite concerns of adverse effects.
13 citations
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June 2019 in “Case reports in dermatology” This report presents the first known case of localized nonscarring and scarring alopecia following autologous fat grafting and reviews literature on alopecia caused by facial fillers, suggesting vascular compromise as a potential cause.
January 2026 in “Dermatologic Therapy” This study reports that intramuscular compound betamethasone may offer rapid, short-term reduction in hair shedding for patients with telogen effluvium, particularly within a week, but often requires repeated treatments; only mild side effects were observed.
December 2016 in “The Journal of Sexual Medicine” This study reviewed the preferences and reasons for testosterone injection therapy among 53 Canadian men with hypogonadism, finding that most opted for injections due to efficacy, ease, and cost considerations.
122 citations
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November 2014 in “BMC Medicine” This research observed that oral testosterone replacement therapy significantly increases cardiovascular risk, while effects of injected or transdermal therapy on cardiovascular risk were not significant, prompting further investigation into these methods.
77 citations
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August 1986 in “Archives of Dermatology” This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
19 citations
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May 2020 in “American journal of men's health” This review discusses androgen therapy in adolescents, detailing current practices and noting the limited use of commercially available testosterone or dihydrotestosterone formulations; no new results are reported.
11 citations
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January 2007 in “Veterinary dermatology” This study found that administerating 10 mg/kg intramuscular fulvestrant did not stimulate hair regrowth in Pomeranian dogs with alopecia X, though higher doses may warrant further investigation.
11 citations
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August 1986 in “Archives of Dermatology” This case report describes a patient with skin and nail hyperpigmentation and premature gray hair due to vitamin B12 deficiency, which were reversed after treatment with cyanocobalamin.
7 citations
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January 2001 in “PubMed” This study found that vitamin B6 injections over several weeks improved hair condition and reduced hair loss in some women with diffuse alopecia, while calcium pantothenate had no clear positive effect.
7 citations
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August 1985 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that subcutaneous injection of medroxyprogesterone acetate was more effective than intramuscular or topical treatments in reducing hair diameter for hirsute females.
5 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
2 citations
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December 2020 in “American Journal of Dermatological Research and Reviews” This study found that combining 308-excimer phototherapy with intramuscular triamcinolone acetonide was effective and well tolerated for treating resistant alopecia totalis, showing a 90% overall response rate in the ten patients studied, with the best results observed in younger patients.
1 citations
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September 2021 in “Skin appendage disorders” This systematic review of five studies found that intradermal and intramuscular botulinum toxin injections showed promising hair growth outcomes for men with androgenic alopecia, but emphasizes caution due to a lack of control groups and small sample sizes.
September 2025 in “Chinese Journal of Plastic and Reconstructive Surgery” This review reports that while botulinum toxin shows potential mechanisms for treating androgenetic alopecia, recent high-quality trials found no significant hair density improvement compared to placebo, indicating it can't yet replace traditional treatments.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 42-year-old man with radiation-induced alopecia following endovascular embolization for a cerebral arteriovenous fistula experienced complete hair regrowth after three months of treatment with intramuscular corticosteroids and topical 5% minoxidil, suggesting a novel therapeutic approach for faster recovery.
2 citations
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July 2022 in “Pediatric dermatology” This case report highlights that a restrictive rice milk diet in a young child led to kwashiorkor with severe malnutrition, skin changes, and developmental regression, which improved with a protein-rich therapeutic diet.
2 citations
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March 2022 in “Laboratory Animal Research” This study suggests that a mild intramuscular dose of botulinum toxin improved spermatogenesis and sperm parameters in ageing mice.
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that a mild intramuscular dose of BOTOX increased spermatogenesis and improved sperm quality in ageing mice, suggesting potential benefits for managing male infertility.
November 2024 in “Nanomaterials” This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.
1 citations
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November 2024 in “Cutis” PLLA injections can cause hair loss and skin issues.
4 citations
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January 2022 in “Drug design, development and therapy” This study demonstrated that intramuscular corticosteroids were effective for severe alopecia areata, with significant hair regrowth in 80.2% of patients, though a high relapse rate was noted post-treatment. Nail involvement and disease duration over six months negatively impacted outcomes.
April 2023 in “Indian journal of paediatric dermatology” In this case study, a 12-year-old boy with isolated nail lichen planus showed significant improvement after receiving intramuscular triamcinolone acetonide and topical tacrolimus treatment, although his great toenails were less responsive.
19 citations
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December 2021 in “Endocrine Reviews” This review highlights therapeutic options for inducing puberty in males and females with delayed puberty, emphasizing the need for larger trials to establish the best approaches.
6 citations
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September 2018 in “International Journal of Molecular Sciences” This study found that intramuscular injections of a PRP-derivative in healthy beagle dogs did not result in statistically significant changes in lumbar muscle tissue or IGF-1 blood concentration, suggesting the treatment may be safe at therapeutic doses.
6 citations
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January 2020 in “The Aging Male” In this study, five-year testosterone replacement therapy improved fasting blood sugar, HbA1c, and triglyceride levels in Japanese hypogonadal men without significantly affecting prostate-specific antigen levels.
January 2025 in “Journal of Dermatological Treatment” This study describes three cases of filler-induced alopecia with hair regrowth observed following treatments, emphasizing the importance of early intervention and understanding anatomical risks during cosmetic filler procedures.
10 citations
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October 1981 in “Archives of Dermatology” This case report describes a 36-year-old man with tinea incognito manifesting as asymptomatic, flat patches of alopecia, which did not improve with standard treatments.