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    Glossary Interleukin-17C

    protein that promotes inflammation and helps fight infections

    Interleukin-17C (IL-17C) is a type of cytokine, which is a protein that cells use to communicate with each other, especially in the immune system. IL-17C plays a crucial role in the body's defense mechanisms by promoting inflammation and helping to fight off infections, but it can also contribute to inflammatory diseases if not properly regulated.

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    1. 413 DC-HIL+ myeloid-derived suppressor cells are elevated in the peripheral blood and lesional skin of cutaneous lupus patients Journal of Investigative Dermatology · 2018
    2. Editors' Picks Journal of Investigative Dermatology · 2012
    3. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis medRxiv (Cold Spring Harbor Laboratory) · 2021 · 114 citations
    4. Secukinumab-Induced Alopecia Areata Successfully Treated with Tofacitinib in a Patient with Palmoplantar Pustulosis Clinical, cosmetic and investigational dermatology · 2023 · 1 citations
    5. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    6. The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis Arthritis Research & Therapy · 2025
    7. Transforming pomelo peel waste into multifunctional biomaterials for hemostasis and wound healing Communications Materials · 2025
    8. Impacto del desequilibrio del microbioma del cuero cabelludo en la severidad de la alopecia areata, marcadores inflamatorios y cambios post-tratamiento Universidad de Córdoba Insitutional Repository (Universidad de Córdoba) · 2025
    9. UNCONVENTIONAL PROTEIN SECRETION OF KERATIN 75 BY AMELOBLASTS IN VIVO D-Scholarship@Pitt (University of Pittsburgh) · 2018
    10. Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair Durham e-Theses (Durham University) · 2014
    11. Pre-clinical non-viral vectors exploited for<i>in vivo</i>CRISPR/Cas9 gene editing: an overview Biomaterials Science · 2022 · 23 citations
    12. Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model Scientific reports · 2019 · 6 citations
    13. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside Frontiers in immunology · 2020 · 144 citations
    14. The Important Role of Leptin in Modulating the Risk of Dermatological Diseases Frontiers in immunology · 2021 · 15 citations
    15. Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study Journal of Clinical Medicine · 2021 · 4 citations
    16. Antiacne and Anti-Inflammatory Effects of Phenolic Compounds from Quercus acutissima Carruth. Leaves Evidence-based Complementary and Alternative Medicine · 2022 · 4 citations
    17. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    18. Evidence on Hidradenitis Suppurativa as an Autoinflammatory Skin Disease Journal of Clinical Medicine · 2024 · 9 citations
    19. Multiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy Allergy · 2025
    20. Ritlecitinib: Efficacy of a Novel Therapy for Severe Alopecia Areata in Patients Aged 12 Years and Older Actas Dermo-Sifiliográficas · 2025
    21. Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases Cell · 2020 · 227 citations
    22. Natural killer cells in atopic and autoimmune diseases of the skin Journal of Allergy and Clinical Immunology · 2010 · 91 citations
    23. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    24. Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia? Journal of Investigative Dermatology · 2016 · 69 citations
    25. 3D bioprinting of integral ADSCs-NO hydrogel scaffolds to promote severe burn wound healing Regenerative Biomaterials · 2021 · 61 citations
    26. Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-α and allergic responses Journal of Allergy and Clinical Immunology · 2021 · 59 citations
    27. RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation 2011 · 42 citations
    28. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    29. IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes 2019 · 32 citations
    30. Alopecia Areata: Pathogenesis, Diagnosis, and Therapies MedComm · 2025 · 21 citations