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    Glossary Inhibition

    process of slowing or preventing a biological reaction

    Inhibition refers to the process of slowing down or preventing a biological reaction or activity. In the context of hair and alopecia, inhibition might involve the suppression of certain enzymes or pathways that contribute to hair loss, thereby potentially promoting hair growth or preventing further hair thinning.

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    1. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations
    2. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep Neuroscience · 2007 · 100 citations
    3. Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition The Journal of Steroid Biochemistry and Molecular Biology · 1997 · 98 citations
    4. Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing Development · 2016 · 87 citations
    5. Inhibition of skin 5α-reductase by oral contraceptive progestins<i>in vitro</i> Gynecological Endocrinology · 2000 · 78 citations
    6. Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies European Journal of Clinical Pharmacology · 2020 · 77 citations
    7. Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility Pharmacology Biochemistry and Behavior · 2007 · 60 citations
    8. Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82 Journal of Investigative Dermatology · 2017 · 53 citations
    9. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation Psychoneuroendocrinology · 2011 · 53 citations
    10. Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells Cells · 2019 · 51 citations
    11. Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients Nutrients · 2017 · 49 citations
    12. Inhibition of 5α‐Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice Alcoholism Clinical and Experimental Research · 2008 · 49 citations
    13. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009 · 47 citations
    14. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice Psychoneuroendocrinology · 2012 · 42 citations
    15. Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition Journal of Investigative Dermatology · 1996 · 42 citations
    16. Inhibition of Wnt/β‐catenin pathway promotes regenerative repair of cutaneous and cartilage injury The FASEB Journal · 2015 · 41 citations
    17. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    18. Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque<sup>1</sup> Endocrinology · 1997 · 33 citations
    19. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    20. INHIBITION OF KERATINIZING STRUCTURES BY SYSTEMIC DRUGS Pharmacological Reviews · 1963 · 32 citations
    21. Inhibition of glycosphingolipid synthesis reverses skin inflammation and hair loss in ApoE−/− mice fed western diet Scientific Reports · 2018 · 30 citations
    22. Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis Acta neuropathologica communications · 2019 · 29 citations
    23. Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes Hormone and metabolic research · 2007 · 29 citations
    24. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    25. Inhibition of CCAAT/Enhancer Binding Protein Family DNA Binding in Mouse Epidermis Prevents and Regresses Papillomas Cancer Research · 2007 · 28 citations
    26. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia European Journal of Pharmacology · 2001 · 28 citations
    27. Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. PubMed · 2003 · 26 citations
    28. Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes <i>In Vitro</i> Hormone and metabolic research · 2007 · 24 citations
    29. Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract Evidence-based Complementary and Alternative Medicine · 2009 · 22 citations
    30. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations