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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.

Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

Lipase H is important for hair follicle function and shaping hair fibers.

A girl inherited excessive body hair from her mother and grandmother.

Immune cells are essential for early hair and skin development and healing.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Only a few hair-specific keratins are linked to inherited hair disorders.

Norwegian puffin dogs have a unique type of hair loss that often doesn't get better on its own and responds well to ciclosporin treatment.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Some scalp sores are linked to different inherited skin conditions.

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

PPCM microspheres allow controlled finasteride release over 24 hours.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.

Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.

More men have Androgenic Alopecia than women, it's often inherited, and stress can contribute to it.

Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

Gene mutations can cause problems in male genital development.