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    Did you mean Inflammatory Pathways?
    Glossary Inflammatory Pathways

    molecular signals triggering the body's response to harmful stimuli

    Inflammatory pathways, also known as inflammatory signaling pathways, are a series of molecular signals and reactions that the body uses to respond to harmful stimuli, such as pathogens, damaged cells, or irritants. These pathways involve various cells and proteins, including cytokines and chemokines, which work together to initiate and regulate inflammation, ultimately aiming to protect and heal the body. Understanding these pathways is crucial for developing treatments for conditions like alopecia, where inflammation can play a significant role in hair loss.

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    1. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    2. The high-polarity fraction of tail fat derived from Lanzhou Fat-Tailed sheep enhances skin wound healing through the regulation of inflammatory factors and the TGF-β1/Smad3 signaling pathway Food Science and Human Wellness · 2026
    3. The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds Cells · 2023 · 9 citations
    4. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1 International Journal of Molecular Sciences · 2023 · 1 citations
    5. Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review) Molecular Medicine Reports · 2021 · 18 citations
    6. Protective effect of a novel metal-phenolic network composite against ultraviolet-induced skin damage by modulating MAPK/AP-1/NF-κB signaling pathways and attenuating oxidative stress in human keratinocytes Biomedicine & Pharmacotherapy · 2025
    7. Bioactive Small Molecule Enhances Skin Burn Wound Healing and Hair Follicle Regeneration by Activating PI3K/AKT Signaling Pathway: A Preclinical Evaluation in Animal Model Journal of Biomedical Nanotechnology · 2022
    8. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    9. Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-β and mitochondrial signaling pathway. PubMed · 2018 · 24 citations
    10. 1341 Possible role of mTOR signaling pathway in radiation dermatitis Journal of Investigative Dermatology · 2023
    11. [Research advances on the mechanism of Wnt/β-catenin signaling pathway in body surface wound healing]. PubMed · 2023
    12. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    13. JAK-STAT pathway-associated skin diseases: a refined functional framework for inflammatory skin diseases Frontiers in Immunology · 2026
    14. Pea Sprout Extract Promotes Hair Follicle Regeneration via Anagen Phase Prolongation and Dual Modulation of Oxidative and Inflammatory Signaling Journal of Microbiology and Biotechnology · 2025
    15. Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways British Journal of Dermatology · 2017 · 27 citations
    16. Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of the <i>ERK 1/2</i> Signaling Pathways Advances in wound care · 2019 · 26 citations
    17. Transcriptomic crossroads: Decoding genes and pathways that connect alopecia areata with chronic inflammatory skin disorders JID Innovations · 2026
    18. Identification of Key Genes and Signaling Pathways in Male Androgenetic Alopecia by Bioinformatics Analysis Bioinformatics and Bioengineering · 2020
    19. The common regulatory pathway of COVID-19 and multiple inflammatory diseases and the molecular mechanism of cepharanthine in the treatment of COVID-19 Frontiers in Pharmacology · 2022 · 15 citations
    20. The Extract of Periplaneta americana (L.) Promotes Hair Regrowth in Mice with Alopecia by Regulating the FOXO/PI3K/AKT Signaling Pathway and Skin Microbiota Current Issues in Molecular Biology · 2025
    21. Alleviation of Androgenetic Alopecia with Aqueous Paeonia lactiflora and Poria cocos Extract Intake through Suppressing the Steroid Hormone and Inflammatory Pathway Pharmaceuticals · 2021 · 4 citations
    22. 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2/HO‐1 signalling pathway Journal of Cellular and Molecular Medicine · 2024 · 1 citations
    23. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    24. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    25. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    26. MON-218 Inflammatory Role of Sex Steroids in Hidradenitis Suppurativa: An Androgenic Phenotype Journal of the Endocrine Society · 2019
    27. Effective amelioration of hepatic inflammation and insulin response in high fat diet-fed rats via regulating AKT/mTOR signaling: Role of Lepidium sativum seed extracts Journal of ethnopharmacology · 2020 · 14 citations
    28. Fruit Acid Inhibits UV-Induced Skin Aging via PI3K/Akt and NF-κB Pathway Inhibition Discovery Medicine · 2025 · 3 citations
    29. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    30. A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models BMC Biotechnology · 2026