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    Glossary Inflammatory Pathways

    molecular signals triggering the body's response to harmful stimuli

    Inflammatory pathways, also known as inflammatory signaling pathways, are a series of molecular signals and reactions that the body uses to respond to harmful stimuli, such as pathogens, damaged cells, or irritants. These pathways involve various cells and proteins, including cytokines and chemokines, which work together to initiate and regulate inflammation, ultimately aiming to protect and heal the body. Understanding these pathways is crucial for developing treatments for conditions like alopecia, where inflammation can play a significant role in hair loss.

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    1. Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals 2019 · 18 citations
    2. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    3. Dracorhodin Perchlorate Regulates the Expression of Inflammatory Cytokines through the TLR4 Pathway and Improves Skin Wound Healing in Diabetic Rats Evidence-based Complementary and Alternative Medicine · 2022 · 4 citations
    4. miR‐200a‐3p in Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes Attenuates UVB‐Induced Skin Inflammatory Response and Oxidative Stress via Keap1‐Nrf2 Pathway Stem Cells International · 2025
    5. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    6. JAK-STAT pathway-associated skin diseases: a refined functional framework for inflammatory skin diseases Frontiers in Immunology · 2026
    7. The high-polarity fraction of tail fat derived from Lanzhou Fat-Tailed sheep enhances skin wound healing through the regulation of inflammatory factors and the TGF-β1/Smad3 signaling pathway Food Science and Human Wellness · 2026
    8. Transcriptomic crossroads: Decoding genes and pathways that connect alopecia areata with chronic inflammatory skin disorders JID Innovations · 2026
    9. The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds Cells · 2023 · 9 citations
    10. i-PRF-Derived Exosomes Promote Hair Regeneration by Modulating Inflammatory, Oxidative, Angiogenic, and Regenerative Pathways in an Androgenetic Alopecia Mouse Model Trends in Sciences · 2026
    11. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside Frontiers in immunology · 2020 · 144 citations
    12. The common regulatory pathway of COVID-19 and multiple inflammatory diseases and the molecular mechanism of cepharanthine in the treatment of COVID-19 Frontiers in Pharmacology · 2022 · 15 citations
    13. Drugs targeting the JAK/STAT pathway for the treatment of immune-mediated inflammatory skin diseases: protocol for a scoping review BMJ Open · 2019 · 17 citations
    14. Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003 · 194 citations
    15. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    16. Alleviation of Androgenetic Alopecia with Aqueous Paeonia lactiflora and Poria cocos Extract Intake through Suppressing the Steroid Hormone and Inflammatory Pathway Pharmaceuticals · 2021 · 4 citations
    17. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1 International Journal of Molecular Sciences · 2023 · 1 citations
    18. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    19. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    20. BH17 Bridging the gap: identifying dual-targeting therapies for patients with alopecia areata and coexisting immune-mediated inflammatory diseases British Journal of Dermatology · 2025
    21. Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance Brazilian Journal of Microbiology · 2026
    22. Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review) Molecular Medicine Reports · 2021 · 18 citations
    23. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    24. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    25. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    26. Fruit Acid Inhibits UV-Induced Skin Aging via PI3K/Akt and NF-κB Pathway Inhibition Discovery Medicine · 2025 · 3 citations
    27. Neuroendocrine Pathways in Skin Health and Homeostasis: A Systematic Review Journal of Dermatology Research · 2026
    28. A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models BMC Biotechnology · 2026
    29. Protective effect of a novel metal-phenolic network composite against ultraviolet-induced skin damage by modulating MAPK/AP-1/NF-κB signaling pathways and attenuating oxidative stress in human keratinocytes Biomedicine & Pharmacotherapy · 2025
    30. CD271 orchestrates skin structure, differentiation, and inflammation via PI3K/Akt and PKCα/ERK pathways Cell Death and Disease · 2025