4 citations
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September 2012 in “Journal of dermatological science” The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
1 citations
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June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.
1 citations
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March 1995 in “JAMA” This text provides no research findings; it is a website's navigation and policy information for JAMA publications.
1 citations
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June 1942 in “JAMA” This article discusses observations about the relationship between baldness and gray hair in middle-aged men, noting that baldness often precedes grayness, and suggests a possible connection to premature aging, but reports no new data.
1 citations
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April 2023 in “Portuguese Journal of Dermatology and Venereology” This review examines the pathophysiological mechanisms and emerging targeted treatments for alopecia areata, particularly highlighting the efficacy of oral JAK inhibitors over other less effective alternatives.
1 citations
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January 2019 in “Advances in stem cells and their niches” This chapter reviews the biology and regulatory mechanisms of epidermal stem cells, emphasizing their heterogeneity and roles in skin homeostasis, cancer, and aging, without reporting new findings.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.
November 2024 in “Biophysical Chemistry” This study analyzed the swelling behavior of human hair during permanent waving treatment, finding that both the microstructure and macrostructure of intermediate filaments swell simultaneously at the initial stage, and while partially destructed by reduction, they are considerably restored through oxidation.
June 2024 in “Journal of the Mississippi State Medical Association” This review article explores common causes of hair loss in female patients, such as autoimmune and hormonal factors, and discusses various diagnostic and treatment approaches, highlighting the potential for permanent hair loss due to untreated inflammation.
This study found that human hair exhibits significant deformation in its intermediate filaments under strain, with recovery taking about 1000 minutes, suggesting a self-healing period post-mechanical stress. Additionally, cuticle scales deform much less than the cortex, and the Poisson ratio aligns with soft matter properties.
This study found that in mice, the epidermal microenvironment reverses the oncogenic effects of GNAQQ209L in melanocytes, inhibiting their survival and proliferation through paracrine signals.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that in women with PCOS in Port Harcourt, Nigeria, glucose homeostatic disorders were common, particularly among those with higher testosterone levels, suggesting the need for glucose disorder screening in this population.
This study found that oxidized hair undergoes time-related structural changes, resulting in improved thermal and mechanical stability over several months after moderate or intense oxidative treatments.
March 2026 in “European journal of ecology, biology and agriculture.” This study found significantly higher levels of Toll-Like Receptor 4, interferon gamma, and interleukin-17 in Iraqi patients with alopecia areata compared to controls, suggesting these immune markers play a crucial role in the disease's development and could be targets for future treatments.
April 2018 in “Journal of Investigative Dermatology” This study found that both Th1 and Th2 cytokine markers were elevated in the serum and skin of patients with alopecia areata, with Th2 markers more closely linked to disease severity.
24 citations
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November 1997 in “Journal of Biological Chemistry” This study found that genes encoding mouse high-glycine/tyrosine proteins show distinct spatial and temporal expression patterns in hair follicles, suggesting diverse protein distribution during hair growth cycles.
2 citations
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December 2025 in “Gels” This study developed a biomimetic 3D skin model with vascularization potential to assess the impact of nano-zinc oxide (nano-ZnO), finding that nano-ZnO significantly influenced genes related to apoptosis, inflammation, and oxidative stress in skin cells.
January 2023 in “Skin appendage disorders” This study's review of existing research found insufficient data to determine the impact of skin type on the effectiveness of low-light laser therapy for hair growth in androgenetic alopecia, with a notable lack of data on darker skin types.
400 citations
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January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.
107 citations
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August 2002 in “Journal of Neurology, Neurosurgery, and Psychiatry” Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
75 citations
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November 2009 in “Gynecological Endocrinology” This study found that both myo-inositol and metformin helped restore normal menstrual cycles in patients with PCOS, but myo-inositol appeared to be more effective in inducing pregnancy.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” This study introduces a method for long-term expansion of adult mouse epidermal stem cells in vitro using an organoid culture system that maintains the basal-apical organization.
66 citations
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September 2008 in “Dermatologic therapy” This review discusses medical treatments for hirsutism, focusing on oral contraceptives and other therapies, but reports no new results; the authors emphasize the lack of evidence for insulin sensitizers in treating hirsutism alone.
66 citations
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June 2004 in “Biophysical Journal” Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
57 citations
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June 2021 in “Science” This study found that women's biomedical patents more often focus on women's health needs, highlighting how inventor representation can influence the diversity of inventions.
53 citations
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September 2013 in “Journal of Investigative Dermatology” This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.
52 citations
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May 2006 in “Journal of Structural Biology” This study identified two key pentapeptide quasi-repeats in human keratin-associated proteins, which are similar to motifs found in sheep wool.
51 citations
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July 2008 in “Dermatologic Therapy” This article proposes two new categories of cicatricial alopecia—“unstable” and “stable”—and suggests surgical excision as preferred over hair transplantation, especially for unstable cases.
46 citations
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May 1997 in “British journal of dermatology/British journal of dermatology, Supplement” Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.
38 citations
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September 2021 in “Signal Transduction and Targeted Therapy” This review discusses genetic factors contributing to susceptibility and outcomes in COVID-19, including ACE, ACE2, TMPRSS2 variants, HLA genotype, and ABO blood group, but reports no new experimental results.