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This research outlines how retinoids, compounds based on vitamin A, activate nuclear receptors to influence cellular processes such as differentiation and carcinogenesis, with benefits like anti-inflammatory properties but requiring careful management of dose-dependent side effects.

This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.

In this case report, half-siblings with bullous congenital ichthyosiform erythroderma were found to have a susceptibility to Trichophyton rubrum infection, successfully treated with oral terbinafine.

Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.

Pre-existing skin conditions and drug reactions are the main causes of exfoliative erythroderma.

This article reviews Netherton syndrome, focusing on its genetic basis, clinical presentation, and treatment options, and reports no clinical results; the authors mention potential benefits of targeted therapies and gene therapy.

This study reviewed the use of dupilumab, beyond its approved indications for atopic dermatitis and prurigo nodularis, and found effective treatment reports for various chronic inflammatory skin diseases such as bullous autoimmune diseases, eczema, and alopecia areata, highlighting its broad potential in dermatology.

This review found that oral JAK inhibitors, used off-label in various inflammatory skin disorders, often resulted in rapid and sustained clinical improvements with acceptable safety over several months, although the evidence is drawn from case-based reports.

This article reports a case of Netherton's syndrome that responded to 12% ammonium lactate lotion, suggesting potential treatment benefits for skin and allergic symptoms in this rare condition.

This review discusses the various roles of vitamin D in skin disorders, including established use in psoriasis and potential applications for atopic dermatitis and skin cancer prevention, but reports no new clinical results.

This review covers the diverse cutaneous and systemic presentations of sarcoidosis in patients with skin of color, emphasizing the importance of early recognition to improve outcomes despite a generally poorer prognosis compared to Caucasians.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

This study found that infections and eczematous conditions were the most common skin disorders across all ages, with acne vulgaris being notably prevalent in adolescents and young adults.

Transplant patients often get skin problems, with treatments varying by condition.

This case report highlights the successful treatment of Kaposi varicelliform eruption in a pemphigus vulgaris patient using intravenous acyclovir, alongside antibiotics, resulting in healing of skin lesions with scarring.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.

This review discusses updates in the genetics and clinical understanding of congenital ichthyosis and highlights the addition of N-acetylcysteine and topical enzyme replacement to the treatment options, without providing new clinical results.

This study reports that tofacitinib, a JAK inhibitor, may stabilize hair loss in patients with classic lichen planopilaris and frontal fibrosing alopecia, though hair regrowth was not robust.

This review discusses various rare syndromes associated with ichthyosis and emphasizes the importance of understanding their molecular genetics and mechanisms for developing effective treatments and genetic counseling, but it reports no new clinical findings.

This index of Harper's Textbook of Pediatric Dermatology, Fourth Edition, provides no clinical results or new findings.

This text is not a research abstract but website navigation and policy information; it provides no study results.

This case report describes a 9-month-old male infant with Netherton syndrome, highlighting the importance of early diagnosis and treatment initiation for better management of symptoms and prevention of misdiagnosis.

This study presents a rare instance of Netherton syndrome diagnosed incidentally in siblings of consanguineous parents, initially misdiagnosed as other skin conditions, emphasizing the need for careful evaluation in chronic skin cases to prevent misdiagnosis.

This case report describes an inflammatory skin reaction linked to kava kava ingestion, with the patient's condition resolving after treatment with oral prednisone and topical hydrocortisone.

This case report describes a 1-month-old male infant with Netherton syndrome, characterized by severe hypernatremia, skin and scalp issues, highlighting the syndrome's complications, including growth retardation and infection risks in early life.

In this retrospective study at a New Delhi children's hospital, the authors found that pediatric skin diseases were most commonly infections and infestations, with bacterial infections and scabies leading, followed by eczemas.

In this study, 13-cis-5S*,8S*-epidioxy-5,8-dihydroretinoic acid was found to be significantly more cytotoxic to cancer cell lines than other retinoic acid analogs evaluated.

This review discusses various nonfollicular scalp conditions causing secondary scarring or permanent alopecia and highlights the importance of specific diagnoses and treatments but reports no new results.

This report describes a woman with borderline lepromatous leprosy who developed a serious skin reaction to dapsone; she recovered quickly after stopping dapsone and receiving corticosteroids.