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    Glossary Hypertrophy

    Hypertrophy refers to the increase in the size of cells, which can lead to the enlargement of tissues or organs. In the context of hair biology, hypertrophy can be relevant when discussing the growth and development of hair follicles, particularly in response to certain stimuli or treatments. Key distinguishing characteristics of hypertrophy include the thickening of hair strands and potential changes in follicle density, which can influence hair density and overall appearance. Understanding hypertrophy is important in hair loss research, as it may provide insights into potential therapeutic approaches for conditions like androgenetic alopecia.

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    1. Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring Stem Cell Research & Therapy · 2021 · 45 citations
    2. WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling Experimental & Molecular Medicine · 2021 · 36 citations
    3. Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice PloS one · 2015 · 32 citations
    4. Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model Stem cell reviews and reports · 2022 · 13 citations
    5. Botulinum Toxin Type A for Preventing Facial Trauma and Hypertrophic Scars: A Meta‐Analysis and Trial Sequential Analysis Journal of Cosmetic Dermatology · 2025
    6. Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis Open Medicine · 2025
    7. Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids International journal of molecular sciences · 2018 · 305 citations
    8. A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar Wound repair and regeneration · 2012 · 47 citations
    9. A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies Wound Repair and Regeneration · 2014 · 35 citations
    10. Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models Bioengineering & Translational Medicine · 2023 · 21 citations
    11. Topical Calcipotriol for Preventive Treatment of Hypertrophic Scars Archives of Dermatology · 2009 · 18 citations
    12. Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model European journal of pharmacology · 2015 · 10 citations
    13. Morphologic and Histologic Comparison of Hypertrophic Scar in Nude Mice, T-Cell Receptor, and Recombination Activating Gene Knockout Mice 2015 · 9 citations
    14. Transcription factor c‐Maf drives macrophages to promote hypertrophic scar formation Journal of Cosmetic Dermatology · 2023 · 5 citations
    15. Hairless Descendants of Mexican Hairless Dogs: An Experimental Model for Studying Hypertrophic Scars Journal of Cutaneous Medicine and Surgery · 2011 · 5 citations
    16. Gut microbiota-derived metabolites in keloid and hypertrophic scarring Frontiers in Microbiology · 2025 · 3 citations
    17. Hypertrophic Scar Formation on Application of Terpenoid Fraction of Tuberous Root of<i>Mirabilis jalapa</i>L. on Excision Wound Model in Wistar Albino Rats International Scholarly Research Notices · 2014 · 2 citations
    18. The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring Pharmaceutics · 2023 · 1 citations
    19. The expression of melatonin receptor in human hypertrophic scar Chinese journal of plastic surgery · 2010 · 1 citations
    20. Dihydromyricetin attenuates fibrosis-associated features of hypertrophic scar with accompanying changes in PI3K/AKT/mTOR-related signaling Frontiers in Pharmacology · 2026
    21. Dermatoscopic Patterns in Keloid, Hypertrophic, and Atrophic Scars: Cross-Sectional Analysis and Clinical Correlation Dermatology Practical & Conceptual · 2025
    22. Pooled, Frozen, Gamma‐Irradiated Amniotic Fluid Enhances Histomorphological Remodelling in Hypertrophic Scars International Wound Journal · 2025
    23. Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis Burns & Trauma · 2025
    24. Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles Interdisciplinary materials · 2025
    25. HYPERTROPHIC GENITAL HERPES IN THE ANAL AND GENITAL REGION MIMICKING ANAL AND VULVAR CARCINOMA: CASE REPORT Journal of Coloproctology · 2024
    26. The effect of inflammatory cytokines on the risk of hypertrophic scar: A Mendelian Randomization Study Research Square (Research Square) · 2024
    27. Addressing Keloid and Hypertrophic Scars from Hair Transplant Journal of Asia Pacific Aesthetic Sciences · 2022
    28. Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C Acta Medica Marisiensis · 2016
    29. Acitretin: A good treatment option for hypertrophic lichen planus Indian journal of drugs in dermatology · 2016
    30. Morphological and distribution characteristics of sweat glands in hypertrophic scar and their possible effects on sweat gland regeneration 中华医学杂志:英文版 · 2005