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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Cathepsin L is essential for normal hair growth and development.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Hair loss severity relates to increased miniaturization in female pattern hair loss.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.