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    Glossary High-Fat Diet

    diet high in fats, often over 35-40% of calories

    A High-Fat Diet (HFD) is a dietary regimen where a significant portion of daily caloric intake comes from fats, often exceeding 35-40% of total calories. This type of diet is commonly used in research to study metabolic disorders, obesity, and their effects on various biological processes, including hair growth and alopecia.

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    1. Effective amelioration of hepatic inflammation and insulin response in high fat diet-fed rats via regulating AKT/mTOR signaling: Role of Lepidium sativum seed extracts Journal of ethnopharmacology · 2020 · 14 citations
    2. Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages Cell reports · 2022 · 6 citations
    3. Yangyin Qingre Huoxue Method in Traditional Chinese Medicine Ameliorates Atherosclerosis in ApoE<sup>−/−</sup> Mice Suffering from High-Fat Diet and HSP65 Aggression Evidence-based Complementary and Alternative Medicine · 2019 · 4 citations
    4. AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS 2024
    5. The role of wood sterol in alopecia induced by high fat diet through lipid metabolism Food bioscience · 2024
    6. 930 High-fat diet exacerbates neutrophilic folliculitis by facilitating sequential chemokine expressions by keratinocytes and neutrophils 2018
    7. Impact of a High-Fat High-Carbohydrate (HFHC) Diet at a Young Age on Steroid Hormone Hair Concentrations in Mice: A Comparison with a Control Diet and Nutraceutical Supplementation Life · 2025
    8. Consumption of a low-carbohydrate and high-fat diet (the ketogenic diet) exaggerates biotin deficiency in mice Nutrition · 2013 · 10 citations
    9. Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet Journal of Hard Tissue Biology · 2024
    10. Protective Effect of “ <i>Ark‐e‐Kasni</i> ,” a Unani Formulation, in Letrozole and High‐Fat Diet–Induced Polycystic Ovarian Syndrome in Rats Journal of obstetrics and gynaecology research · 2026
    11. Hypoglycemic activity of extracts of Chamaecyparis obtusa var. formosana leaf in rats with hyperglycemia induced by high-fat diets and streptozotocin Journal of Traditional and Complementary Medicine · 2019 · 10 citations
    12. 477 Dietary fat- and obesity-sensitive dermal adipocyte PKCβ induction and inflammation cross-talk Journal of Investigative Dermatology · 2017
    13. Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19 International Journal of Molecular Sciences · 2021 · 3 citations
    14. Diet‐Induced Obesity Promotes Alopecia Through Oxidative Stress and Androgen Signalling in Female Mice Experimental Dermatology · 2026
    15. Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity PLOS ONE · 2019
    16. Recovery of a Vietnamese Child from Impaired Fasting Glucose and Hyperinsulinemia After one Year of Implementation of an Appropriate Diet Plan: A Case Report Biomedical Journal of Scientific & Technical Research · 2021
    17. Polycystic Ovary Syndrome (PCOS) and Other Androgen Excess–Related Conditions: Can Changes in Dietary Intake Make a Difference? Nutrition in Clinical Practice · 2008 · 48 citations
    18. Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota Frontiers in Physiology · 2022 · 1 citations
    19. Milestones in Photocarcinogenesis Journal of Investigative Dermatology · 2013 · 29 citations
    20. Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease Frontiers in Immunology · 2022 · 9 citations
    21. Clinical characteristics and factors associated with different BASP subtypes of androgenetic alopecia Frontiers in Medicine · 2026
    22. The Association of Polycystic Ovarian Syndrome Among Reproductive-Aged Women With Consumption of Junk Food in Jeddah, Saudi Arabia Curēus · 2023
    23. Alleviation of hyperlipidemia, insulin resistance, and myopathy by nano selenium/ nano CoQ10 platform with simvastatin in hyperlipidemic rats; comprehensive outlook Research Square (Research Square) · 2023
    24. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism Journal of Lipid Research · 2018 · 45 citations
    25. Role of Nutritional Diversity and Lifestyle in Polycystic Ovary Syndrome (PCOS) Risk among College Students: A Cross-Sectional Analysis of Mumbai Metropolitan Region, India Journal of Scientific Research and Reports · 2025
    26. 752 Diet and the dermal white adipose tissue: Analyzing shifts in the cutaneous lipid landscape in response to dietary change 2020
    27. Fatty acid composition of selected organs of gerbils maintained on a fat‐deficient or fat‐supplemented diet Lipids · 1977 · 4 citations
    28. The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat-High-Fructose-Induced Insulin Resistance Swiss-Webster Male Mice Journal of Experimental Pharmacology · 2025
    29. The effect of dietary change on in vitro erythrocyte haemolysis, skin lesions and alopecia in common marmosets (Callithrix jacchus) Comparative biochemistry and physiology. A. Comparative physiology · 1991 · 7 citations
    30. Inhibition of glycosphingolipid synthesis reverses skin inflammation and hair loss in ApoE−/− mice fed western diet Scientific Reports · 2018 · 30 citations