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Metreleptin Treatment in a Boy with Congenital Generalized Lipodystrophy Due to Homozygous c.465_468delGACT (p.T156Rfs*8) Mutation in the BSCL2 Gene: Results From the First Year

research Metreleptin Treatment in a Boy with Congenital Generalized Lipodystrophy Due to Homozygous c.465_468delGACT (p.T156Rfs*8) Mutation in the BSCL2 Gene: Results From the First Year

1 citations, June 2022 in “JCRPE”

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ

218 citations, October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

research The Paradox of p53: What, How, and Why?

64 citations, July 2016 in “Cold Spring Harbor Perspectives in Medicine”

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

research Do Different Diagnostic Criteria Impact Polycystic Ovary Syndrome Diagnosis for Adolescents?

16 citations, December 2017 in “Journal of Pediatric and Adolescent Gynecology”

Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.

research Metabolic Syndrome: A New Definition and Management Guidelines

11 citations, December 2022 in “Arterial Hypertension”

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

research Co-Administration of 5α-Reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids

8 citations, June 2020 in “The Journal of Clinical Endocrinology and Metabolism”

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial

research Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial

7 citations, January 2022 in “Evidence-based complementary and alternative medicine”

Ginger supplements helped reduce symptoms and improve metabolic health in hypothyroid patients.

research Increase in Subcutaneous Adipose Tissue in the Frontal Scalp May Be Associated With Androgenetic Alopecia and Metabolic Syndrome

June 2023 in “PubMed”

Thicker scalp fat may link hair loss with metabolic syndrome.

research Metabolic Syndrome – A New Definition and Management Guidelines: A Joint Position Paper by Various Polish Medical Societies

20 citations, August 2022 in “Archives of Medical Science”

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

research Shortcutting the Diagnostic Odyssey: The Multidisciplinary Program for Undiagnosed Rare Diseases in Adults (UD-PrOZA)

8 citations, May 2022 in “Orphanet Journal of Rare Diseases”

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

research Keratin 79 Is a PPARA Target That Is Highly Expressed by Liver Damage

1 citations, January 2023 in “Biochemical and biophysical research communications”

Keratin 79 is linked to liver damage and may help diagnose liver diseases.

research Gynostemma Pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth via the Wnt/Beta-Catenin Pathway

March 2024 in “Nutrients”

Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.

Prevalence of Non-Alcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and Its Correlation with Metabolic Syndrome

research Prevalence of Non-Alcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and Its Correlation with Metabolic Syndrome

35 citations, May 2015 in “Arquivos De Gastroenterologia”

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.